Hydroxypyl methylcelose (hpmc) littattafan polymer na halitta da aka saba amfani dashi a cikin abinci, magani, kayan kwaskwarima da sauran filayen. Hankalinta muhimmin mai nuna alama ne yana shafar aikinsa, wanda yawanci yana da alaƙa da abubuwan kwayoyin cuta kamar nauyin kwayar cutar HPMC, irin haɗuwa da haɗuwa da zazzabi.
1. Nauyi mai nauyi
Nauyin kwayar cutar HPMC yana daya daga cikin mahimman abubuwan da suka shafi danko. Gabaɗaya magana, mafi girma ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cutar HPMC, mafi muni da danko. Wannan saboda tsarin macromelectularular na samar da ƙarin ma'amala na Macromoleculle ƙarin intmolekululadulular, wanda ya haifar da takunkumi mai ƙarfi akan ruwan mafita. Sabili da haka, a daidai maida hankali, mafita hpmc tare da manyan kwayoyin kwayoyin yawanci suna nuna mafi girma vicoosities.
Karuwa a cikin nauyin kwayoyin yana rinjayar da kaddarorin viscoelics na mafita. Hanyoyin HPMC tare da manyan ƙwayoyin ƙwayoyin cuta suna nuna Visceralttationasashen Viscoelitir na ƙananan karfi, yayin da a mafi girman ƙimar karfi da za su iya rawa kamar ruwayen jarirai. Wannan ya sa HPMC suna da mahimman halayen rholologir cikin yanayin abubuwan amfani daban.
2. Bayani na bayani
Taro na maganin yana da tasiri mai mahimmanci akan danko na HPMC. Kamar yadda maida hankali ne ga HPMC yana ƙaruwa, hulɗa tsakanin kwayoyin halittar a cikin mafita yana ƙaruwa, sakamakon ƙara haɓakar juriya don haka ƙara danko. Gabaɗaya magana, maida hankali ne game da HPMC yana nuna haɓakar rashin daidaituwa tsakanin wani kewayon da ba shi da ƙarfi, wato, da ƙima wanda aka girmama shi tare da maida hankali a hankali.
Musamman ma a cikin mafita na iyawa, ma'amala tsakanin sarƙar kwayar cuta ta fi ƙarfi, da tsarin cibiyar sadarwa ko kuma gelation na iya faruwa, wanda zai ƙara haɓakar ƙwayoyin mafita. Saboda haka, a aikace-aikacen masana'antu, don samun ingantaccen kulawa ta danko, sau da yawa ana zama dole don daidaita taro na HPMC.
3. Nau'in sauran
Karatu da danko na HPMC suna kuma alaƙa da nau'in abubuwan da aka yi amfani da shi. HPMC yawanci tana amfani da ruwa a matsayin sauran ƙarfi, amma a ƙarƙashin wasu takamaiman yanayi, wasu abubuwan da aka gyara kamar ethanol da acetone kuma ana iya amfani da su. Ruwa, a matsayin polar da aka kera, na iya yin ma'amala da karfi tare da hydroxyl ƙungiyoyi da metyl ƙungiyoyi a cikin kwayoyin halitta don inganta rushewarsa.
Polarity na da yawa, zazzabi, da kuma ma'amala tsakanin da sauran ƙarfi da kwayoyin halittar HPMC zasu shafi warwarewar da danko na HPMC. Misali, lokacin da ake amfani da ƙarancin ƙarfi-polarity, ƙwayoyin hpmc yana raguwa, wanda ya haifar da ƙananan danko.
4. Zazzabi
Tasirin zazzabi a kan danko na HPMC shima yana da matukar muhimmanci. Gabaɗaya, danko na bayani hpmc na raguwa tare da ƙara yawan zafin jiki. Wannan saboda lokacin da zazzabi ya karu, motsin kwayoyin da motsin kwayoyin ke ƙaruwa, yana haifar da rauni game da karfin gwiwa, don haka rage danko.
A wasu nau'ikan zazzabi yakai, da rhological kaddarorin bayani ba bayyananne ba ne, wato kariyar ba ta shafi canje-canje da zazzabi ba ya shafa. Saboda haka, a aikace-aikace aikace-aikace, sarrafa canje-canje na zazzabi yana ɗaya hanyar ingantacciyar hanya don daidaita danko na HPMC.
5. Shear kudi
Dalilin bayani HPMC ba ya cutar da abubuwan da suka shafi tsayayye, har ma ta hanyar karancin kai. HPMC ruwa ne wanda ba Newtian bane, kuma danko yana canzawa tare da canjin karfi na kudi. Gabaɗaya magana, Maganin HPMC ya nuna kyakkyawan danko a ƙarancin ƙimar kai, yayin da danko ya ragu sosai a manyan ragin. Wannan sabon abu ana kiranta Shear Thinning.
Tasirin karfi na karfi a kan danko na HPMC mafi yawanci yana da alaƙa da halayen kwararar sarƙoƙi na kwayoyin. A ƙananan ƙididdigar karfi, sarkar kwayoyin kwayoyin halitta suna aiki tare, haifar da ingantaccen danko; A mafi girman ƙimar ƙura, hulɗa tsakanin sarƙoƙin kwayoyin cuta kuma danko ya ɗan rage ƙasa.
6.
Maganin HPMC shima yana da alaƙa da darajar pH na mafita. Kwayoyin halitta HPMC suna ɗauke da daidaitattun Hydroxypyl da metyl ƙungiyoyi, kuma cajin jihar waɗannan rukunoni sun shafa da PH. A wasu ph sun tarar, kwayoyin HPMC na iya ionize ko samar da gels, ta haka canza danko.
Gabaɗaya, a cikin yanayin alkyabbar acidic ko kuma HPMC na iya canzawa, ya shafi ma'amala da kwayoyin halitta kuma, bi da bi, shafi dankan. A dabi'un pH daban-daban, kwanciyar hankali da rheology na Sallolin HPMC na iya bambanta, ya kamata a biya musamman kulawa ta PH yayin amfani.
7. Tasiri da ƙari
Baya ga abubuwan da suka shafi abubuwan da ke sama, wasu ƙari kamar salts da Surfactant suna iya shafar danko na HPMC. Bugu da kari na gishiri na iya canza shi na ionic karfi na mafita game da bayani, ta hanyar karuwa da kariyar kwayoyin kwayoyin HPMC. Surfacts na iya canza tsarin kwayar cutar hpmc ta canza ma'amala tsakanin kwayoyin, ta haka canza danko.
Magani na HPMC ya shafi abubuwa da yawa, ciki har da nauyin kwayoyin, irin wannan yanayin, zazzabi, mai ƙima da ƙari. Don sarrafa halayen kayan haɗin gwiwa na HPMC, waɗannan dalilai suna buƙatar ƙididdige ma'ana daidai gwargwadon buƙatun aikace-aikacen. Ta hanyar fahimtar wadannan abubuwan more iya ingancin HPMC a cikin samarwa da abubuwan amfani da abubuwan amfani da abubuwa don tabbatar da kwanciyar hankali da tasirin amfani da su a aikace-aikace daban-daban.
Lokaci: Feb-15-2025