Shiri da kaddarorin Hydroxypyl methylcelose

Methypyl methylcelose(HPMC) kayan polymer na halitta tare da albarkatu mai yawa, sabuntawa, da kuma kyakkyawan ruwa da kuma kayan aikin fim. Abu ne mai kyau kayan albarkatun kasa don shirye-shiryen fina-finai mai narkewa.

Fim mai narkewa ruwa mai narkewa shine sabon nau'in kayan marafi, wanda ya sami kulawa mai yawa a Turai da Amurka da sauran ƙasashe. Ba wai kawai amintaccen aiki don amfani ba, amma kuma yana magance matsalar ɗaukar kayan sharar gida. A halin yanzu, kayan finafinan ruwa mai narkewa suna amfani da kayan aikin man fetur kamar polyvinyl barasa da polyethylene opyvinyl da polyethylene opyvinyl da polyethylene opyvinlene azaman kayan abu. Petroleum hanya ce da ba a iya ba da ita, kuma amfani-girma-sikelin-sikelin zai haifar da ƙarancin albarkatu. Hakanan akwai fina-finai mai narkewa ruwa da ruwa kamar sitaci da furotin kamar su albarkatu, amma waɗannan finafinan ruwa mai narkewa suna da kyawawan kayan aikin injin. A cikin wannan takarda, sabon nau'in farantin ruwa mai narkewa da aka shirya ta hanyar amfani da hanyar samar da hanyar samar da hanyar samar da kayan fim ɗin ta amfani da hydroxypypropyl methylcellulose kamar albarkatun kasa. Sakamakon maida hankali kan ruwa-samar da fim ɗin HPMC da zazzabi-forming a kan tenarfafa fina-finai da aka tattauna fina-finai na hpmc ruwa mai narkewa. An yi amfani da glycitol, dan wasan sorutaraldehydehyye an kara inganta aikin fim mai narkewa ruwa na hpmc ruwa. A ƙarshe, don faɗaɗa aikace-aikacen fim mai narkewa a cikin marufi na abinci, an yi amfani da ganye na aob don inganta kaddarorin antioxidant fim mai narkewa ruwa mai narkewa. Babban binciken kamar haka:

(1) tare da karuwar taro na HPMC, ƙarfin tenarancin ƙarfafawa a hutu na HPMC ya karu, yayin da hasken transmtance ya ragu. Lokacin da HPMC maida hankali ne 5% kuma fim ɗin forming zazzabi ne 50 ° C, cikakkiyar kaddarorin fim ɗin HPMC sun fi kyau. A wannan lokacin, karfin daukaka ke kusan 116pta, elongation a karya kusan kashi 31%, lokacin watsa wutar shine 90%, kuma lokacin disarin narkar da ruwa shine 55min.

(2) Glycerolers da Sorbitol Ingantaccen Inganta kayan aikin na HPMC, wanda muhimmanci ya karu da elongation a hutu. Lokacin da abun ciki na glycerros yana tsakanin 0.05% da 0.25%, sakamakon shine mafi kyau, kuma elongation a cikin fim ɗin hpmc ruwa ya kai kusan 50%; Lokacin da abun ciki na Sorbitol shine 0.15%, elongation a karya yana ƙaruwa zuwa 45% ko haka. Bayan an canza fim ɗin hpmc ruwa mai narkewa da glycerol da kuma ɗan ƙasa, ƙarfin ƙarfi da abubuwan da ba su da kyau sun ragu, amma raguwar ba mahimmanci ba.

(3) Spectory Spectroscopy (ftir) na glutaraldellet-coverlided hpmc ruwa fim ya nuna cewa glutaraldealde na fim-mai narkewa da ruwa mai narkewa. Lokacin da ƙari da ƙari na Glutaralde ya kasance 0.25%, kayan aikin na kayan aiki da kayan adon finafinan sun kai mafi kyawun yanayin. Lokacin da ƙari da ƙari na Glutaralde ya kasance 0.44%, lokacin da aka lalata ruwa-disolewa ya kai 135 min.

(4) Azzabin da ya dace na AOB zuwa cikin HPMC ruwa mai narkewa mai narkewa na iya inganta mafita na maganin antioxidant na fim. A lokacin da 0.03% aka kara AOB, da AOB / HPMC fim din yana da ƙima na kusan kashi 89% don AOB, wanda ya kasance yana inganta aiban HPMC ba tare da inganta ba.

Kalmomin key: fim mai narkewa na ruwa; Hydroxypyl methylcelos; filastik; wakili mai haɗi; Antioxidant.

Tebur na abubuwan da ke ciki

Takaitawa ..................................... ....................................................................................

Abstract .......................................................................................................

Tebur na abubuwan da ke ciki ........................... ... ...................................................................

BABI NA GOMA SHAFI .................................................................................. ...........................................................................................................

1.1Water- soluble film……………………………………………… ……………………………………………… …………….1

1.1.1 -. PVAPLYVINYL (PVA) Fim mai narkewa ....................................... 1

1.1.2.2ppalyhylene oxide (peo) fim mai narkewa .............................. ..2

1.1.3starch-tushen fim mai narkewa na ruwa mai narkewa .........

1.1.4 Fail-tushen fina-finai-slokle ............................................................................................................................................................................................................................................................................................................................................................................................................................................................. .2

1.2 hydroxypyl methylcellose ...........................................................................................

1.2.1 Tsarin Hydroxypropyl methylcellulose ..........................................................3

1.2.2 Ruwa na Ruwa na Hydroxypropyl methylcellulose ................................ 4

1.2.3 fim-forming Properties of Hydroxypropyl methylcellulopyl methylcellulopyl methylcellulose ..................................4

1.3 Canza Canza Canza Hydroxypoyl Methylcellulopyl Methylcellulopyl Methylcellulopyl ...........................4

1.4 Canjin Hymants na Haɗin Hydroxypropyl methylcellulopyl methylcellulopyl ........................ .5

1.5 Abubuwan AntioxIDative na Hydroxypropyl methylcellulopyl methylcellulophropyl met methylellose fim .............................................................................................................................................................................................................................................................................................................................................. 5

1.6 Shawara na taken ............................................ .................................... .7

1.7 Bincike Bincike ........................................................................................................................................................................................................................7

Fasaha na 2 Shirihu 2 Shiri da kaddarorin methyp selpyl sel slyl methyl sel methyl fim .......

2.1 Gabatarwa ..................................................................................... ... 8

2.2 Sashe na Gwaji ...................................................... .................................. .8

2.2.1 Abubuwan gwaji da kayan aikinta ................. ......... ..8

2.2.2 Shirye-shiryen Shiryawa ................................................................................... ..9

2.2.3 Halin da Gwajin Aiwatarwa .................................................................................................................................................................................................

2.2.4 sarrafa bayanai ....................................... ........................................................................ 10

2.3 Results da Tattaunawa .........................................................................................

2.3.1 Tasiri na samar da bayani na fim akan fina-finai na bakin ciki .......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 10

2.3.2 Tushen zafin jiki na samar da fim akan fina-finai na hpmc .............................................................................................................................................................13

2.4 Takaitawa Takahi ......................................................................... 16

BABI NA 3 Tasirin filastik a kan fina-finai na hpmc ruwa .............................................17

3.1 Gabatarwa .................................................................................... 17

3.2 Sashe na Gwaji ...................................................................................17

3.2.1 Abubuwan gwaji da kayan aiki ...............................................................

3.2.2 Abubuwan da ake buƙata na samfuri ...........................................................

3.2.3 Halin da Gwajin Aiwatarwa ...................................................................................... .18

3.2.4 Data Data .................................................... ........................... ..19

3.3 Sakamakon da Tattaunawa .................................................................. 19. 19

3.3.1 Sakamakon Glycerol da Sorbitol a bayan wasan kwaikwayo na karin haske na HPMC na bakin ciki .........

3.3.2 The effect of glycerol and sorbitol on the XRD patterns of HPMC thin films ……………………………………………………………………………………………………………………………………..20

3.3.3 Sakamakon Glycerol da Sorbitol a kan kayan aikin na HPMC na bakin ciki .........

3.3.4 Effects of glycerol and sorbitol on the optical properties of HPMC films………………………………………………………………………………………………………………………………………22

3.3.5 The Trust of Glycerol da Serbitol a kan ruwa soli na HPMC fina-finai .......... 23

3.4 Takaitawa na 3.4 .....................

BABI NA 4 sakamakon wakilan masu fasahar ruwa a fina-finai na hpmc ruwa ................................................................................................................................................................................................................................................ 25

4.1 Gabatarwa ..................................................................................... 25

4.2 Sashe na Gwaji ............................................................................ 25

4.2.1 Abubuwan gwaji da kayan aiki ........................................... 25

4.2.2 Shirye-shiryen Shiryawa ........................................................... ..26

4.2.3 Halin da Gwajin Aiwatarwa ................................................................................ .26

4.2.4 Data Data .................................................................. .................................26

Sakamako na 4.3 da Tattaunawa .......................................................................................

4.3.1 Betrarru na shan zaki na karin haske na glutrackyde-crossanked HPMC

4.3.2 Tsarin XD.2 na HPMC na bakin ciki na HPMC

4.3.3 Sakamakon glutaralde a kan kayan aikin ruwa na HPMC ....................... ..28

4.3.4 Sakamakon glutaralde a kan kayan aikin na HPMC na bakin ciki ... 29

4.3.5 Sakamakon glutaralde a kan abubuwan da kayan gani na fina-finai na HPMC ........................9

4.4 Takaitawa ....................................................................... 30

BABI NA 5 Antioxidant HPMC RPMC ruwa fim ...........................................................................................................................................................................................................31

5.1 Gabatarwa ...................................................................................

5.2 Sashe na Gwaji .....................................................................................

5.2.1 Abubuwan gwaji da kayan gwaje-gwaje .............................................................

5.2.2 Pototen Shiryawa ......................................................................32

5.2.3 Halin da gwajin aikin .......................................................................................................................................................................................................

5.2.4 Data Data .................................................................................................. .......................................... 33

5.3 sakamakon da bincike ..........................................................................................33

5.3.1 Ft-Iron Bincike .......................................................................... 33

5.3.2 Chard na Bincike .....................................................................................................................................................................34

5.3.3 Kayayyakin Kayayyaki ...................................................................................................................................................................................................................................................................................

5.3.4 Ruwa na ruwa ........................................................................................35

5.3.5 kaddarorin inji ...........................................................................................................................................................36

5.3.6 Aptical VIDE ................................................................................................7

5.4 Takaitawa na 5.4 ........................................................................................37

Fasali na 6 Gaba ɗaya .......................................... .................................................39

Nasso'i ................................................................................................ 40

Abubuwan bincike yayin karatun digiri ..................................................................................................44

Yarda ..............................................................................................................46

BABI NA GOMA GASKIYA

A matsayin sabon labari mai shirya abu, ana amfani da fim mai narkewa ruwa mai narkewa a cikin marufi daban-daban samfurori a cikin ƙasashen waje (kamar Amurka, Japan, Faransa, da sauransu, da sauransu) [1]. Fim mai narkewa, kamar yadda sunan ya nuna, fim ɗin filastik wanda za'a iya narkar da shi cikin ruwa. An yi shi ne da kayan kwalliyar ruwa mai narkewa wanda zai iya narkewa cikin ruwa kuma ana shirya shi ta hanyar takamaiman tsarin samar da fim. Saboda kaddarorinta na musamman, ya dace sosai ga mutane su shirya. Saboda haka, masu bincike da yawa sun fara kula da bukatun kare muhalli da dacewa [2].

1.1 fim mai narkewa

A halin yanzu, finafinan ruwa mai narkewa sune fina-finai mai narkewa ta amfani da kayan polyvinyl da polyethylene amfani da kayan shaye-shaye ta amfani da abubuwa na halitta, da sitaci.

1.1.1 polyvinyl barasa (pva) fim mai narkewa

A halin yanzu, mafi yawan farin finafinan ruwa mai narkewa a cikin duniya ana narkar da fina-finai na PVA fina-finai. PVA polyl polyler ne da za a iya amfani da shi ta hanyar ƙwayoyin cuta da tushen makamashi, kuma ana iya bazu a ƙarƙashin farashin mai, kyawawan abubuwan da ke haifar da gas, kayan shagar gas [4]. Fim na PVA yana da kyawawan kayan aikin injin, karancin karuwa da kyakkyawan kare muhalli. An yi amfani da shi sosai kuma yana da babban digiri na kasuwanci. Yana da nisa mafi yawan amfani da kuma mafi girman kayan kwalliyar ruwa mai narkewa a kasuwa [5]. PVA yana da watsarancin watsewa kuma za'a iya rushe shi ta hanyar ƙwayoyin cuta don samar da CO2 da H2O a cikin ƙasa [6]. Yawancin bincike akan fina-finai-sluble fina-finai yanzu shine a canza su da cakuda su don samun finafinan ruwa mai narkewa. Zhao Linlin, Xiong Hashange [7] Nazarin shirye-shiryen fina-finai mai narkewa tare da pva, glycerol 16%, sodium Dodecyl sulfate (SDS) 4%. Bayan bushewa na fim ɗin da aka samu, lokaci mai narkewa ruwa a cikin ruwa a ɗakin zazzabi ne 101s.

Kuna hukunta yanayin bincike na yanzu, ana amfani da fim ɗin PVA fim sosai, ƙarancin tsada, da kyau kwarai a cikin kaddarorin daban-daban. Yana da mafi kyawun kayan aikin ruwa mai narkewa a yanzu. Koyaya, a matsayin kayan da aka tsara na man fetur, PVA ba za a iya sabunta hanya ba, kuma ana iya ƙazantar da tsarin sa. Kodayake Amurka, Japan da sauran kasashe sun lissafa shi a matsayin abu mara guba, har yanzu amincinsa yana buɗe tambaya. Duk inhalation da shigarwar suna cutarwa ga jiki [8], kuma ba za a kira cikakken sunadarai kore ba.

1.1.2 polyethylene oxide (peo) fim mai narkewa

Polyethylene opyethylene, wanda kuma aka sani da polyethylene opyethburne opy, therbole polymer wanda za'a iya hade da ruwa a kowane rabo a cikin dakin da zazzabi [9]. Tsarin tsari na polyethylene oxide ne h - (- och2ch2-) n-oh, da kuma kwararar kwayar tasa zata shafi tsarin sa. Lokacin da nauyin kwayoyin yana cikin kewayon 200 ~ 20000, ana kiranta polytylene glycol (Peg), da kuma nauyin kwayoyin ana iya kiranta 20,000. Peo babbar farin fillular foda, wanda yake mai sauƙin aiwatarwa da tsari. Fina-finai na peo yawanci ana shirya su ta hanyar ƙara filastik, masu kwalliya da talla don POO suna iya ta hanyar aiki mai ƙarfi [11].

Fim na Peo fim ne mai narkewa mai ruwa mai kyau a halin yanzu, kuma kayan aikin injin din ma yana da kyau, amma yana da yanayin lalacewa mai wahala, wanda ke da wasu tasirin lalata. PVA fim din fim [12]. Bugu da kari, Pet kuma yana da cancantar rashin cancanta, saboda haka da wuya a yi amfani dashi a cikin kayan aikin kayan [13].

1.1.3 sitaci-tushen fim mai narkewa

Starch shine babban kwayoyin polymer na halitta, kuma daruruwan sa suna dauke da babban adadin kungiyoyin Hydroxyl, saboda haka wurin da sitaci yana da wuya a narke da aiwatarwa, kuma da wuya sitaci ba shi da wahala, kuma yana da wuya a yi hulɗa da sauran polymers. sarrafa tare [14,15]. Solyarfin ruwa na sitaci ba shi da kyau, kuma yana ɗaukar lokaci mai tsawo don kumbura cikin ruwan sanyi, don haka sitaci mai narkewa, ana amfani da sitaci mai narkewa, ana amfani dashi don shirya fina-finai mai narkewa. Gabaɗaya, sitaci yana ƙididdigewa ta hanyar hanyoyin da aka haɗa da su kamar haɗuwa, ETRArting, grafting, da kuma inganta ruwa-da-7,16].

Gabatar da eth ether a cikin ƙungiyoyin sitaci ta hanyar sinadarai na iya lalata ko kuma amfani da sitaci na sitaci don kyautata yanayin fim [17], da kuma sandar sandar santsi tare da ingantattun kayan fim. Koyaya, a ƙarancin zafin jiki, fim ɗin sitaci yana da kyawawan kayan kayan aikin injin da talauci, saboda haka a mafi yawan lokuta, da darajar amfani da PVA, kuma ainihin darajar amfani ba ta da yawa.

1.1.4 Jawo tushen-mai narkewa mai narkewa

Protein shine wani abu mai mahimmanci na kimiyyar lissafi mai aiki wanda ke cikin dabbobi da tsire-tsire. Tun da yawancin abubuwan gina jiki sune insoluble cikin ruwa a dakin da ake yi a cikin zazzabi a dakin da zazzabi da kayan ruwa kamar yadda kayan. Don inganta karancin sunadarai, suna buƙatar gyara. Hanyoyin sunadarai na yau da kullun sun haɗa da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta, phthaloisation, phosphtance, da sauransu. [18]; Tasirin gyara shine canza tsarin nama na furotin, ta yadda ta karu da ƙima, gemu, masu aiki kamar su sha da kwanciyar hankali suna biyan bukatun samarwa da sarrafawa. Za'a iya samar da fina-finai mai narkewa ta hanyar amfani da samfurin aikin gona da kuma taksi mai ban sha'awa kamar gashin kai, ko kuma kayan masarufi ne a kan muhalli [19]. Koyaya, fina-finai mai narkewa da matrix iri ɗaya ne kamar yadda matrix suna da kyawawan kaddarorin kayan aikin injin da zazzabi, don haka yancin aikace-aikacen su ya kunkuntar.

Don taƙaita, yana da muhimmanci muhimmanci don haɓaka sabon, mai sabuntawa, ruwa mai narkewa, ruwa mai narkewa don haɓaka finafinan ruwa mai narkewa na yanzu.

Hydroxypyl methyl sel (hydroxypropyl methyl selululose, abu ne kawai na halitta polymer, amma kuma ba shi da haɗari, ba da izini ba, ba a iya tsoratar da wadataccen albarkatu a yanayi [20]]. Yana da kayan abinci mai kyau da kayan kwalliya na fim, kuma yana da yanayin shirya fina-finai mai narkewa.

1.2 hydroxypyl methylcelose

Rydroxypyl methyl SirRulose A ruwa mai narkewa mai ruwa mai narkewa [21]. Hydroxypyl methylcellulise yana da halaye masu zuwa:

(1) mai yawa da sabuntawa. Raw kayan methypypropyl methylcellulose ne mafi yawan sananniyar halitta na halitta a duniya, wanda mallakar albarkatun kwayoyin halitta ne.

(2) tsabtace muhalli da kuma biodegradable. Hydroxypyl methylcelose ne wanda ba mai guba ba ne kuma mara lahani ga jikin dan adam kuma ana iya amfani dashi a cikin magani da masana'antar abinci.

(3) kewayon amfani. A matsayin kayan kwalliya mai ruwa mai narkewa, hydroxypropyl methylcelrose yana da kyau solifile ruwa, watsawa, da sauran kayayyaki, kuma ana iya yin amfani da shi a cikin kayan abinci da sauran filayen masana'antu [21].

1.2.1 Tsarin Hydroxypyl methylcelose

An samo HPMC daga sel na halitta bayan Alkaliyama, da wani ɓangare na polyydroxypropyl ethyl sun cika da provylene opylene oxide da methyl chloride. Babban Janar HPMC Methyl Subchangta na Methyl ya samo asali daga 1.0 zuwa 2.0, da kuma hydroxypropyl matsakaiciyar canji mataki daga 0.1 zuwa 1.0. An nuna tsarin kwayoyin jikinsa a cikin Hoto na 1.1 [22]

Saboda haɗin hydrogen mai ƙarfi tsakanin fitlilin na halitta macromeeleces, yana da wuya a narkewa cikin ruwa. Dalilin fitilun seluloofied cikin ruwa yana inganta sosai saboda an gabatar da kungiyoyin ether, wanda ke lalata shaidu a cikin ruwa [23]]. Hydroxypyl methylcelose (HPMC) Hydroxyl-alkyroxylalal alyl alyl alyl alyl alyl alyl alyl alyl alyl alyl ne na yau da kullun (-OCHAopypropoxoxy (-och3), hydroxyproproxy (-och3), hydroxyproproxy (-och3), hydroxyproproxy (-och3), hydroxypoloxoxy (-och3), hydroxypoloxoxy (-och3), hydroxypoloxoxy (-och3), hydroxypholoxoxy (-Och3), hydroxypolose dim (-och3), hydroxypyl ƙungiyoyi. ELEVers ingantacciya ce ta daidaitawa da gudummawar kowane rukuni. - [Och2ch (ch3)] n oh da hidimar hydroxyl a karshen N OH rukuni wani rukuni ne mai aiki, wanda ke da tiyata ta ciki ta hanyar Macritecular Cikin Gida; -Och3 rukuni ne na ƙarshen, shafin amsawa shafin zai kasance a ɓoye bayan canzawa, kuma yana cikin ɗan gajeren ƙungiya-tsararre [21]. Kungiyoyin Hydroxyl akan sabon sarkar reshe ta kara da kungiyoyin hydroxyl sun rage a kan ragowar glucose na sama, wanda ya haifar da ingantaccen tsarin hadaddun abubuwa a tsakanin kewayon makamashi [24].

1.2.2 Staility Ruwa Na Rydroxypropyl methylcelhin

Hydroxypyl methylcellose yana da kyawawan kaddarorin saboda na musamman tsarinsa, mafi sanannen abin da shine karfinsa ruwa. Yana kumbura cikin ingantaccen bayani a cikin ruwan sanyi, da kuma maganin yana da takamaiman aikin, babban gaskiya da aikin tsayayye [21]. Hydroxypyl methypze ne ainihin ethulose ethere ethere an gyara shi bayan methylellulose an gyara shi da ruwa karfin ruwa, don haka har yanzu yana da halaye na methylellling maimaitawa da ruwa; Methyl Slellulicke yana buƙatar sanya shi a 0 zuwa 5 ° C na mintina 20 zuwa 40 don samun mafita mai kyau da kuma danko mai kyau [25]. Iya warware matsalar hydroxypropyl methylcellulhopyl kawai yana buƙatar zama a 20-25 ° C don samun kyakkyawan kwanciyar hankali [25]. Misali, pulverezed hydroxypyl methylcellulopyl methylcellulopyl methylcellulopyl methylcel 0.2-0.5 mm) Za a iya narkar da sauƙi a cikin ruwa a ɗakin karatu 4% na ruwa a cikin 20 ° C.

1.2.3 fim-forming Properties of Hydroxypropyl methylcellullose

Magani Hydroxypyl methylcelo bayani yana da kyau kwarai fina-finai, wanda zai iya samar da kyawawan halaye ga shafi shirye-shirye na magunguna. Manufofin fim ɗin da aka kafa ta ba shi da launi, kamshi, mai tauri da rashin gaskiya [21].

Yan Yanzhong [26] Amfani da gwajin Orthogonal don bincika kayan fim-forming of Hydroxypropyl methylcellulose. Ana aiwatarwa da bincike a kan matakai uku tare da taro daban-daban da abubuwan da suka shafi daban-daban a matsayin abubuwan da dalilai. Sakamakon ya nuna cewa ƙara 10% hydroxypropyl methylcellulopyl methyol bayani yana da mafi kyawun kayan fim-samar da fina-finai, kuma ana iya amfani dashi azaman fina-finai na saki.

1.1 Canza Canza Canza Methyllulopyl Methylcellulopyl Methylcellulopyl Methylcellulopyl

A matsayinka na hanya mai tsari na halitta, fim ɗin da aka shirya daga Cellulose a matsayin albarkatun kasa yana da kwanciyar hankali da sarrafawa, kuma shine da lahani ga mahallin. Koyaya, fina-finai masu fina-finai marasa daidaituwa suna da ƙarancin tashin hankali, da kuma seluloose za a iya noma da filastik.

[27] Amfani da Triethyl Citrate da Acetyl Tetsetryl citrate don dasa shuru da kuma gyara pelulose pelulose perpulose. Sakamakon binciken ya nuna cewa elongation a hutu na sel acetate an karu da 36% da 50% lokacin da taro na Traistl Citrate Citrate ya kasance 10%.

Al [28] etcerolers na filastik Glycerers, stearic acid da glucose metirylcellulose membranes. Sakamakon da aka nuna cewa yawan adadin ƙwayar Methyl ya kasance mai kyau lokacin da abun glycane ya fi na 1.5%, da kuma ilongation rabo na abun ciki na glucose da stearic acid 0.5%.

Glycerol mai launi ne mai launi, mai daɗi, bayyananne, ruwa mai laushi tare da dandano mai daɗi, wanda aka fi sani da glycerin. Ya dace da nazarin hanyoyin mafita, masu safiya, filoli, da sauransu za'a iya narkar da shi da ruwa a cikin kowane irin abu don moisturize fata. Sorbubol, farin hygroscopic foda ko crystalline foda, flakes ko granules, ƙanshi mai kamshi. Yana da ayyukan danshi sha da riƙe ruwa. Dingara kadan a cikin samar da danko da alewa zai iya ci gaba da abinci mai taushi, inganta kungiyar da rage tauraruwa da wasa da yashi. Glycerol da Serbitol suna da abubuwa masu narkewa mai ruwa-ruwa, wanda za'a iya haɗe shi da pera ruwa mai narkewa. Ana iya amfani dasu azaman filastik don sel. Bayan ƙara, zasu iya inganta sassauci da elongation a hutun fina-finai. [29]. Gabaɗaya, maida hankali ne ga mafita shine 2-5%, kuma adadin filastik shine 10-20% na celulaka ether. Idan abun ciki na filastik ya yi yawa, phenomage phenonon na Colloid Dishydration zai faru a babban zazzabi [30].

1.2 Canjin Hydroxypyl methylcellulloos fim

Fim mai narkewa yana da kayan abinci mai narkewa, amma ba a sa ran zai narke cikin sauri lokacin da aka yi amfani da shi a wasu lokatai ba, kamar su jakar cocaging jaka. Tsaba suna lullube shi da fim mai narkewa, wanda zai iya ƙara yawan rayuwa ta tsirar tsaba. A wannan lokacin, don kare tsaba, ba a sa ran fim ɗin zai narke cikin sauri ba, amma fim ɗin ya kamata ya fara taka leda a cikin tsaba. Sabili da haka, ya zama dole don tsawanta lokacin lokacin ruwa mai narkewa na fim. [21].

Dalilin da ya sa Hydroxypolyl methylellulopyl methyllulose yana da kyau socultilationungiyoyi na Hydroxyl-hydroxypyl ƙungiyoyi greendl Hydroxyl hydroxypropyl rukuni Methylcellulose an rage, don haka ya rage yawan kayan ruwa na fim din methyllulose fim, wanda zai iya inganta kaddarorin sunadarai na fim zuwa wani lokaci. Alderydes giciye-da aka haɗa tare da hydroxypropyl methylellulose sun hada da glutaraldehyde kungiyoyi biyu, da kuma hadar da hadewar kwastomomi ne da aka saba amfani da shi. Yana da lafiya sosai, haka ana amfani da glutaraldehyde azaman wakilin haɗin yanar gizo na Ethers. Adadin wannan nau'in mai haɗin haɗi na kariya a cikin mafita gabaɗaya 7 zuwa 10% na nauyin ether. Zazzabi na magani shine kusan 0 zuwa 30 ° C, kuma lokacin shine 1 ~ minti 120 [31]. Haɗin haɗin haɗi yana buƙatar aiwatar da shi a ƙarƙashin yanayin acidic. Da farko, acid mai ƙarfi acid ko acid na ƙwayar ƙwayar cuta ko acid ɗin ƙwayoyin cuta an ƙara shi don daidaita PH na mafita don aiwatar da haɗin haɗin haɗi [32]. Are acid da aka yi amfani da HCL, H2SO4, acetic acid, citric acid, da makamantansu. Hakanan za'a iya ƙara acid da alkybiyde a lokaci guda don yin maganin da ke tattare da hanyar haɗin haɗi a cikin Lange na Lukuruka [33].

1.3 Abubuwan Antioxifis na Hydroxyphropyl methylcellullopyl methylcellulpulo fina-finai

Hydroxypyl methyplulose ne wadatacce a cikin albarkatu, mai sauƙin samar da fim, kuma yana da kyakkyawan sakamako mai kyau. A matsayinmu na abinci, yana da babban tasirin ci gaba [34-36].

Zhuang Rongyu [37] Amfani da Hydroxypolyl Methylcellulopyl Methylcel, Fim na ALDO, sannan a adana shi a cikin days 20 ° C na tsawon lokaci a kan kankanin tumatir da launi. Sakamakon yana nuna cewa wahalar tumatir tare da HPMC shafi ya fi wannan ba tare da shafi. An kuma tabbatar da cewa fim mai samar da hpmc zai iya jinkirta da canza launi na tumatir daga ruwan hoda zuwa ja lokacin da aka adana shi a 20 ℃.

[38] Tasirin Hydroxypropyl methylcellulopyl methylcellulopyl methylcelsis (hpmc) Dokar da anthooxylin "Wuzhong" na "Wuzhong" Bayry a lokacin ajiya. Sakamakon da aka nuna cewa aikin antidation na antidation na Bayri da aka bi da shi tare da HPMC fim ya ragu, kuma sakamakon 5% HPMC fim ne mafi kyau.

Wang Kaiki et al. [39] Amfani da "Wuzhong" Bayrywa na gwaji don nazarin sakamakon 'ya'yan itace da' yan anthylcellulars (HPMAC) shafi na Posthissant (hpmc) shafi na Posthissant (hpmc) shafi na Posthissant (hpmc) shafi na Posthissant (hpmc) shafi na Posthissant (hpmc) shafi na Posthissant (hpmc) shafi na Posthissant (HPMAC) shafi na Posthissant (HPMAC) shafi na Posthissant (HPMAC) shafi na Posthyllulose (HPMAC) shafi na Methylellulopyl hadaddun methylellulophropyl hadaddun methylellulophropyl hadaddun methylellulophropyl hadaddun methylellulophropyl hadaddun methylelluloprovet sakamakon aiki. Sakamakon ya nuna cewa riboflavin-mai rufi na hpmc-mai rufi na 'ya'yan itace na farko ko hpmc shafi na lalata, don haka tsawanta lokacin ajiya na' ya'yan itacen.

A cikin 'yan shekarun nan, mutane suna da buƙatu masu girma da mafi girma don amincin abinci. Masu bincike a gida kuma kasashen waje sun canza bincikensu nazarin su daga karin kayan abinci don tattara kayan. Ta hanyar ƙara ko spraying antioxidants a cikin kayan haɗawa, zasu iya rage haduwa da haduwa da abinci. Sakamakon lalacewa [40]. Anwar antioxidants na zahiri sun damu sosai saboda babban aminci da kuma tasirin kiwon lafiya a jikin mutum [40,41].

Antoxidant na ganye bamboo (AROB na gajere) shine na asali antioxidant kamshi creampence compamcce da kuma ingantaccen ƙarfin ruwa. An jera shi a cikin ƙimar ƙasa GB2760 kuma an yarda da Ma'aikatar Lafiya kamar maganin antioxidant don abinci na zahiri. Hakanan za'a iya amfani dashi azaman abinci mai ƙari don samfuran nama, samfuran ruwa da abinci mai narkewa [42].

Sun Lina da sauransu. [42] Duba manyan abubuwanda kaddarorin bambo ganye antitoxidants kuma sun gabatar da aikace-aikacen ganye na bamboo ganye antitixidants a cikin abinci. Dingara 0.03% AOB zuwa sabon mayonnaise, tasirin antioxidanant shine mafi fili a wannan lokacin. Idan aka kwatanta da adadin adadin shayi polyphenol antioxidants, tasirin antioxidanant a bayyane yake fiye da na shayi polyphenols; Dingara 150% zuwa giya a MG / L, kaddarorin Antioxidant da kwanciyar hankali na Antoxidant da kwanciyar hankali tare da jikin giya. Duk da yake tabbatar da ingancin ingancin jikin giyar, shi ma yana haɓaka ƙanshi mai ƙanshi da ɗanɗano dandano na bamboo [43].

A taƙaitaccen bayani, Hydroxypropyl methylcellulose yana da kyawawan kayan fim-kirkirar kuma kyakkyawan aiki. Hakanan abu ne mai launin kore da ƙira, wanda za'a iya amfani dashi azaman fim ɗin kwantena a fagen kunshin [44-48]. Glycerol da Sorbitol sune kayan filastik ruwa mai narkewa. Dingara glycerol ko dan wasan fim-kirkirar bayani-samar da ingancin hydroxypyl methylcellulopyl Methylcellulopyl fim, ta haka ya kara elonglulose fim [49-51]. Glutaraldehaldectich ake amfani da shi. Idan aka kwatanta da sauran alkyabbai, yana da lafiya sosai, kuma yana da rukunin masu ban dariya a cikin kwayar halittar, da kuma saurin haɗawa da kewayawa yana da sauri. Ana iya amfani dashi azaman haɗin haɗin haɗi na hydroxypropyl methylcellulose fim. Zai iya daidaita hanyar samar da fim ɗin, don a iya amfani da fim ɗin a cikin ƙarin lokutan [52-55]. Dingara bamboo ganye antioxidants antit methyplulopyl methylceloselyl methylellose fim don inganta kayan antioxypolyl methylcellulopheryl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl methylcellulopyl

1.4 Shawara na taken

Daga yanayin bincike na yanzu, fina-finai-mai narkewa na ruwa ana haɗa shi da finafinan pva, fina-finai, fina-finai, sitaci-tushen fina-finai-mai narkewa da furotin ruwa-yanki mai narkewa. A matsayin kayan aikin man fetur, PVA da Peo suna da sauran albarkatu, da kuma samar da kayan amfanin gona na iya ƙazantar. Kodayake Amurka, Japan da sauran kasashe sun lissafa shi a matsayin abu mara guba, har yanzu amincinsa yana buɗe tambaya. Duk inhalation da shigarwar suna cutarwa ga jiki [8], kuma ba za a kira cikakken sunadarai kore ba. Tsarin samar da sitaci da kayan ruwa mai narkewa mai santsi bashi da wata lahani kuma samfurin yana da lafiya, amma suna da rashin nasara na samar da fim mai wuya, da kuma yawan juyawa, da kuma saukarwa mai sauƙi. Saboda haka, a mafi yawan lokuta, suna bukatar su shirya ta hanyar hada da wasu kayan kamar PVA. Darajar amfani ba ta da yawa. Saboda haka, yana da matukar muhimmanci a samar da sabon, mai sabuntawa, ruwa mai narkewa, ruwa mai narkewa don inganta matakan fim na yanzu.

Hydroxypyl methylcelropheryp abu ne na polymer na halitta, wanda ba shine kawai arziki cikin albarkatu ba, har ma da sabuntawa. Yana da kayan abinci mai kyau da kayan kwalliya na fim, kuma yana da yanayin shirya fina-finai mai narkewa. Sabili da haka, wannan takarda na yi niyyar shirya sabon nau'in kayan kwalliyar ruwa mai narkewa tare da hydroxypropyl methylcellulose kamar albarkatun ƙasa da rabo, kuma tsara kayan aikin da suka dace (glycerol da man instirolol). ), wakilin haɗin kai (glutaraldehyde), antioxidant (bamboo ganye ganye antioxipyl tare da mafi munin kaddarorin, pictical properties. Fim na ruwa mai narkewa mai ruwa mai narkewa yana da mahimmanci ga aikace-aikacen sa azaman kayan fim mai narkewa.

1.5 Binciken Bincike

Binciken abubuwan bincike kamar haka:

1) Fim mai narkewa-hpmc ruwa mai narkewa da hanyar samar da hanyar samar da fim ɗin fim-forming da yawan zafin jiki na fim mai narkewa.

2) Don yin nazarin sakamakon glycitol da kuma kayan filastik a kan kayan aikin injin, solicelonan ruwa da kuma kayan aikin fina-finai na hpmc ruwa mai narkewa.

3) Don nazarin tasirin haɗakar Grisaralde giciye a cikin ruwa na ruwa, kaddarorin na kayan aiki da kayan aikin fina-finai na hpmc ruwa mai narkewa.

4) Shirye-shiryen AOB / HPMC ruwa mai narkewa. Juriya na iskar shaka, solubility na ruwa, kaddarorin na optical da aka yi nazarin fina-finai na hpmc.

Fasali na 2 Shiri da kaddarorin Hydroxypropyl Methyl Sel Soluhulouke fim mai narkewa

2.1 Gabatarwa

Hydroxypyl methylcelrose ne na halitta sel na asali. Ba mai guba ba ne, ba a sake gurbata ba, sabuntawa, mai haɗa shi, masu arian ruwa, kuma yana da kayan abinci mai kyau da kuma samar da fim. Yana da yiwuwar kayan fim mai narkewa.

Wannan babi zai yi amfani da hydroxypyl methylcellulopyl methylcelose a matsayin albarkatun kasa don shirya maganin ruwa mai narkewa, naptical, da kuma kayan aiki mai narkewa. An nuna kaddarorin fim na fim ɗin, da kuma ƙarfin tensing, elongation da haze da hydroxypropyl prethyplulox ruwa, Expongical gwajin gwajin ruwa da karfin ruwa.

2.2 Ma'aikatar Gwaji

2.2.1 kayan gwaji da kayan aiki

2.2.2 Tsarin Wanthimen

1) Yin nauyi: auna wani adadin hydroxypropyl methylcellulopyl methylcellulopyl methylcellulose tare da daidaitaccen lantarki.

2) Rage: ƙara yadudduka hydroxypyl methylcellilyl Membrane ruwa. Tsira a 2%, 3%, 4%, 5% da 6%.

3) Tsarin fim: ① Shiryawa na kayan fim daban-daban na samar da fim daban-daban. A hydroxypyl methylcellulopyl methyllulo fim mai narkewa na 25-50 μm an shirya shi, kuma fim ɗin yana pereled kuma sanya shi a cikin busasshen akwatin don amfani. Exreparation na bakin ciki fina-finai a cikin yanayi-formings (yanayin zafi a lokacin bushewa da kuma samar da fim a cikin zafi daban-daban (30 ~ 70 ° C) Fim ɗin an bushe shi a cikin tanda na bushewa iska. An shirya fim ɗin hydroxypyl methylcellin ruwa mai narkewa tare da kauri daga 45 μm an shirya shi, kuma an sanya fim ɗin da sanya shi a cikin busasshen akwatin don amfani. A shirye ke da hydroxypyl methylcellulop ruwa fim ana magana ne a matsayin fim fim na HPMC na takaice.

2.2.3 hali da kuma ma'aunin aiki

2.2.3.1 manyan-kusurwa-rayayyen x-ray (xrd) bincike

Worl-kwana difrirgrams (XRD) nazarin yanayin crystalline na wani abu a matakin kwayoyin. An yi amfani da X-Ray wanda aka samar da kamfanin kamfanin Throbo Arl a Switzerland ya yi amfani da hukuncin. Yanayin ma'auni: Maza na X-ray ya kasance cikin layin CU-Kα Line (40kv, 40ma). Kwanayen binciken yana daga 0 ° zuwa 80 ° (2θ). Binciken sauri 6 ° / min.

2.2.3.2 Kayayyakin injiniyoyi

Ana amfani da karfin da elongation da elongation a hutu na fim ɗin ana amfani da su azaman ka'idodin yin hukunci da kayan aikin injin dinta, da kuma Fasali da fim ɗin yana samar da matsi na filayen filastik, kuma naúrar da ke samar da MPA. Elongation a cikin karya (karye elongation) yana nufin rabo daga elongation lokacin da fim ya karye zuwa tsayin asali, ya bayyana a cikin%. Ta amfani da Instron (5943) Rubuta karamin kayan gwajin na duniya na Masana'antu (Shanghai), 50% Hanyar GB130-92-92 Hanyar da aka yi wa tsayin filastik da kuma farfajiya a farfajiya ba tare da an gwada su ba.

2.2.3.3 Pictical Pictionties

Abubuwan da ke da nuna alama mai nuna alama ce ta fina-finai na fina-finai, akasarinsu har da transmitance da haze of fim. A juyawa da kuma haze of fina-finai an auna ta amfani da transttance Haze Tester. Zaɓi samfurin gwaji tare da farfajiya mai tsabta kuma babu creases, a hankali sanya shi a kan kofin harkar zazzabi (25 ° C da 50% RH). Ana gwada samfurin sau 3 kuma an dauki matsakaicin matsakaita.

2.2.3.4 Siyarwa ta ruwa

Yanke wani 30mm × 30mm fim tare da kauri na kusan 45μm, ƙara 100ml na ruwa zuwa ga mai ruwa na 200ml, kuma auna lokacin don ɓacewa gaba daya [56]. An auna kowane samfurin sau 3 kuma an dauki matsakaicin matsakaita, kuma naúrar ta kasance min.

2.2.4 sarrafa bayanai

An aiwatar da bayanan gwaji da kuma makirci da kayan asali software.

2.3 sakamakon da tattaunawa

2.3.1.1 Al'ada Xrd na Fina-Fina-gyare na HPMC a karkashin Tsararren Fina-Finan fim daban-daban

Figal.1

Shafin kewayon kusurwa-kwana shine bincike game da yanayin yanayin abubuwan da ake ciki a matakin kwayoyin. Hoto na 2.1 shine Xrd Divgraction Tsarin Fina-finai na HPMC a karkashin fina-finai daban-daban na samar da ingantaccen bayani. Akwai sandunan rarrabuwa biyu [57-59] (kusa da 9.5 ° da 20.4 °) a cikin fim ɗin HPMC a cikin adadi. Ana iya gani daga adadi wanda tare da karuwar taro na HPMC, kololuwar yaduwar fim kusa da 9.5 ° da 20.4 ° na farko ° an fara inganta. Kuma daga nan ya raunana, mataki na tsarin kwayoyin halitta (tsari da aka umarce shi) na farko ya ƙaru sannan ragewa. Lokacin da aka maida hankali ne 5%, tsarin da aka yi oda na kwayoyin HPMC shine mafi kyau duka. Dalilin da abin da ya shafi abin da ke sama na iya zama tare da karuwar taro HPMC, yawan Crystal Nuclei a cikin fim-kirkirar bayani, don haka yin wani tsari na HPM more yau da kullun. Lokacin da HPMC ta wuce 5%, XR ta rarrabewa da girman girman fim na fim ɗin ya raunana. Daga wani ra'ayi game da tsarin sarkar kwayoyin, lokacin da aka tattara na HPMC na samar da ingantaccen bayani don motsawa kuma ba za a iya shirya shi da yawa ba.

2.3.1.2 Kayayyakin injiniyoyi na tsinkaye na hpmc a karkashin manyan kayayyaki daban-daban.

Ana amfani da ƙarfi da elongation da elongation a karya fim ɗin a matsayin ka'idodin yin hukunci da kayan aikin injin ɗin da fim ɗin yana haifar da matsi na filastik. Elongation a karya shine rabo na gudun hijira zuwa asalin tsawon fim a hutu. Matsayi na kayan aikin injin na fim na iya yin hukunci a aikace-aikace a wasu filayen.

Fig.

Daga Fig. 2.2, canza yanayin ƙarfin ƙarfi da elongation a lokacin hutu na HPMC ya karu da farko na ingantaccen bayani na HPMC samar da bayani na HPMC. Lokacin da aka warware matsalar shine 5%, kaddarorin na inji na fina-finai na HPMC sun fi kyau. Wannan saboda lokacin da fim ɗin samar da ruwa mai ruwa yana ƙasa, ƙwararrun masanin ya ƙasa, don haka hulɗa tsakanin sarƙoƙin kwayoyin cuta ba shi da ƙarfi, saboda kayan aikin crystallizir na fim ba shi da rauni; Lokacin da fim ɗin-samar da hankali ruwa maida hankali ne 5%, kaddarorin na yau da kullun sun kai darajar darajar; Kamar yadda maida hankali ne daga cikin ruwa-kirkirar ruwa ya ci gaba, sakamakon tawaye da yaduwar mafita na fim da aka samu HPMC da kuma lahani na kayan aikin da aka samu [60], sakamakon shi a cikin kaddarorin da aka samu na fina-finai. Sabili da haka, taro na 5% na samar da fim ɗin HPMC shine mafi dacewa. Aikin fim din da aka samu shima ya fi kyau.

2.3.1.3 Abubuwan Pictical Pictions na fina-finai na bakin ciki a ƙarƙashin nau'ikan samar da ingantaccen fim

A cikin fage fina-finai, haske Transttance da kuma haze mahimman sigogi ne masu mahimmanci suna nuna ma'anar fassarar fim. Hoto na 2.3 yana nuna yanayin canji da haze na fina-finai na HPMAC a ƙarƙashin tsararraki na samar da ruwa ruwa. Ana iya gani daga adadi wanda tare da karuwar maida hankali kan mafita na HPMC, juyawa daga cikin HPMC fim a hankali ya ragu sosai tare da karuwar maganin fim-kirkirar bayani.

Fig.2.

Akwai manyan dalilai guda biyu: na farko, daga hango yawan taro na tarawa, lokacin da maida hankali ya ragu, yawan adadin yana da babban tasiri a kan abubuwan da kayan gani na kayan [61]. Sabili da haka, tare da karuwar taro na samar da fim ɗin HPMC, ana rage yawan kayan aikin fim. Haske mai haske ya ragu sosai, kuma ingancin ya karu sosai. Na biyu, daga nazarin tsarin aikin samar da fim, yana iya zama saboda fim ɗin da aka sanya fim ɗin da mafita hanyar samar da hanyar samar da fim. Theara a cikin wahalar elongation yana haifar da ragewar sandar fim ɗin da raguwar abubuwan da abubuwan gani na fim ɗin HPMC.

2.3.1.4 Sosiri na ruwa na bakin ciki na hpmc a karkashin fina-finai daban-daban fim

Solubility na ruwa na fina-finai mai narkewa yana da alaƙa da taro-samar da fim ɗinsu. Yanke fina-finai 30mm × 30mm × 30mm × 30mm fannoni daban-daban na samar da fim, kuma yi alama fim tare da "+" don auna lokacin don ɓatar da fim gaba ɗaya. Idan fim ɗin ya rufe ko sandunansu zuwa ganuwar beaker, sake saitawa. Hoto na 2.4 shine yanayin fasahar ruwa na kayan aikin hpmc a ƙarƙashin jerin ruwa daban-daban. Ana iya gani daga adadi wanda tare da karuwar taro mai ruwa-inabare ruwa, kayan aikin ruwa mai narkewa na fina-finai na HPMC ya ragu. An tantance dalilin cewa dalilin na iya kasancewa tare da samun ingantaccen bayani na HPMC, sakamakon da ke haifar da rauni na HPMC a cikin ruwa da raguwa a cikin ruwa mai narkewa.

Siffa

2.3.2 Tushen yawan zafin fim akan fina-finai na bakin ciki

2.3.2.1 Al'ada Xrd na Fina-finafin HPMC a fina-finai daban-daban fim

Fig

Hoto na 2.5 yana nuna ƙirar XRMC ta bakin ƙasa ta HPMC a fina-finai daban-daban na yanayin zafi. Kwakwalwa biyu naƙasasshe a 9.5 ° da 20.4 ° an bincika don fim ɗin HPMC. Daga hangen nesa na karancin kololuka, tare da karuwar fim ɗin samar da fim, wanda ya raunana ya raunana sannan ya ragu. Lokacin da fim ɗin-forming zazzabi ya kasance 50 ° C, tsarin da aka ba da umarnin da aka ba da umarnin hpmc, lokacin haɓakar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta, da kuka yana da wuya; A matsayinka na fim-forming zazzabi a hankali yana ƙaruwa, yawan ƙarfin haɓaka, motsi na sarkar sarkar a cikin tsari mai tsari; Idan zazzabi fim ya yi yawa, motsin kwayoyin halitta ya yi ƙarfi sosai, da samuwar haɓakar makaman nukiliya ba ta ƙasa ne kuma yana da wahala a samar da lu'ulu'u [62,63]. Sabili da haka, lu'ulu'ar da aka yi game da HPMAC Fina-finai yana ƙaruwa da farko sannan kuma yana raguwa da karuwar zazzabi na fim.

2.3.2.2 Kayayyakin injiniyan na HPMC na bakin fina-finai a cikin fim daban-daban na fim

Canjin fim ɗin forming zazzabi zai sami takamaiman matakin tasiri a kan kaddarorin kayan aikin fim na fim. Hoto na 2.6 yana nuna canji na tensal da elongation a hutu na HPMAC a cikin fim daban-daban fim forming yanayin zafi. A lokaci guda, ya nuna yanayin da farko ya fara fara sannan ragewa. Lokacin da fim ɗin yake yin zafin jiki ya kasance 50 ° C, ƙarfin ƙarfin da elongp ya kai ga matsakaicin ƙimar, wanda ya kamata 116 MPa, bi da bi, bi da bi.

Siffa

Daga hangen dabaru, mafi girma tsarin tsarin kwayoyin, mafi kyawun ƙarfin tensile [64]. Daga HOTAL. 2.5 XRD PATGERS na fina-finai na HPMC a yanayin zafi daban-daban na fim, ana iya ganin wannan tsarin da aka tsara na HPMC na farko yana ƙaruwa sannan ya ragu. Lokacin da zazzabi fim ɗin ne 50 ° C, matsayin tsari na tsari shine mafi girma, don haka ƙarfin ƙarfin fina-finai na HPMAC da farko yana ƙaruwa da yawan zafin jiki, kuma matsakaicin darajar yana bayyana a fim ɗin forming zafin jiki na 50 ℃. Elongation a hutu yana nuna yanayin da farko sannan ragewa. Dalilin na iya zama da karuwar zazzabi, tsarin da aka tsara tsari na farko yana ƙaruwa sannan ya ragu, da kuma tsarin crymer.com ya watse a cikin matrix mara amfani. A cikin Matrix, an kafa tsarin da aka kirkira na jiki, wanda ya taka rawa a cikin Toughening [65], da hakan ne ta bayyana elongp na fim na 50 ° C.

2.3.2.3 Abubuwan Pictionptical Pictical na Fina-finai na HPMC a cikin fim ɗin fim daban-daban

Hoto na 2.7 shine canjin canji na popical kaddarorin finafinai na HPMC a cikin fim na samar da yanayin zafi. Ana iya ganin shi daga adadi wanda tare da karuwar zazzabi na fim, watsa a fim ɗin HPMC a hankali yana ƙaruwa, da kuma abubuwan da abubuwan da suka dace na fim ɗin HPMC a hankali zama mafi kyau.

Siffa

A cewar tasirin zazzabi da kwayoyin ruwa a kan fim [66], lokacin da yawan ruwa ya kasance cikin hpmc a hankali, da HPMC yana cikin yanayin gilashin. The volatilization na fim ɗin siffofin fim ɗin a HPMC, sannan kuma watsa shi ne a ramuka bayan haske [67], saboda haka hasken bayyanar fim ya karaya kuma haze tana da yawa; Kamar yadda zafin jiki yana ƙaruwa, sassan kwayoyin na HPMC sun fara motsawa, da ramuka suka ragu, da kuma yanayin watsa hankali na fim ɗin yana ƙaruwa da hauhawar farashin fim.

2.3.2.4 Maganin ruwa na fina-finai HPMC a cikin fim na samar da yanayin zafi daban-daban

Hoto na 2.8 yana nuna hanyoyin da ruwa na ruwa na fina-finai na HPMC a yanayin zafi daban-daban. Ana iya ganinsa daga adadi da ruwa lokacin Siyasa na HPMC na ƙara yawan zafin fim, wato, hanyar samar da ruwan hpmc na muni. Tare da karuwar zazzabi-samar da zazzabi, ana hanzarta yawan kwayoyin halittar ruwa, da kuma tsarin kwayoyin halitta yana ƙaruwa da kwayoyin halittar ruwa don shiga tsakanin kwayoyin HPMC. Hakanan ana rage kariyar ruwa.

Siffa-fim

2.4 Takaitacciyar Tattaunawa

A wannan babin, hydroxypropyl methylcelcele an yi amfani dashi azaman albarkatun kasa don shirya fim mai narkewa ta hanyar hanyar magance hanyar samar da fim ɗin bayani. An bincika lu'ulu'u na fim na HPMC ta hanyar zaɓi na XRD; Abubuwan da ke da kayan aikin na hpmc ruwa mai narkewa an gwada su kuma ana bincika su ta hanyar na'urar tazarin kayan gwaje-gwaje ta hanyar lantarki ta duniya, da kuma abubuwan da aka kawo abubuwan da aka kawo sunayensu na HPZC na HPZE Tester. Lokacin rushewa a cikin ruwa (lokacin ƙwallan ruwa) ana amfani dashi don bincika kayan aikinta na ruwa. Wadannan zabin da suka zaba ana jan su daga binciken da ke sama:

1) Abubuwan da ke cikin kayan finafinan HPMAC na farko sannan suka ragu tare da karuwar maganin fim, kuma da farko karuwa sannan ya ragu da karuwar zazzabi-forming. Lokacin da maida hankali ne daga cikin fim-kirkirar bayani shine 5% kuma zafin jiki-forming zazzabi ne 50 ° C, kayan aikin injin na fim suna da kyau. A wannan lokacin, ƙarfin da ke ƙasa kusan 116pta ne, kuma elongation a hutu kusan 31%;

2) Abubuwan da kayan gani na finafinan hpmC sun ragu tare da karuwar taro na samar da ingantaccen bayani, a hankali kuma ƙara hankali tare da karuwar zazzabi-forming; A bayyane yake cewa maida hankali ne ga maganin samar da fim ɗin kada ya wuce 5%, kuma zazzabi-foring zazzabi kada ya wuce 50 ° C

3) Ruwa na ruwa na fina-finai na HPMC ya nuna ƙasa-ƙasa tare da karuwar taro na samar da fim ɗin-forming zazzabi. A lokacin da maida hankali ne na 5% na samar da fim na HPMAC-forming da zazzabi-foring zazzabi na 50 ° C aka yi amfani da shi, lokacin da ke narkewa lokacin fim ya 55 min.

Babi na 3 sakamakon filastik a kan fina-finai na hpmc ruwa mai narkewa

3.1 Gabatarwa

A matsayin sabon nau'in kayan polymer na halitta hpmc ruwa mai narkewa yana da kyakkyawan sakamako mai haɓaka. Hydroxypyl methylcelrose ne na halitta sel na asali. Ba mai guba bane, ba mai gurbata, sabuntawa, emolical m, kuma yana da kaddarorin kyau. Ruwa-narkewa da samar da fim, yana da yiwuwar kayan aikin fim mai narkewa.

Babin da ya gabata ya tattauna shirye-shiryen fim mai narkewa ta hanyar amfani da hydroxypropyl meting na samar da ruwa mai kyau methylcellulopoyl fim mai narkewa. aiwatar da tasiri. Sakamakon ya nuna cewa ƙarfin fim ɗin kusan 116mpta da elongation a hutu shine 31% a ƙarƙashin ingantaccen taro da yanayin tsari. Tauyin irin wannan fina-finai ba shi da kyau a cikin wasu aikace-aikacen da kuma bukatun ci gaba.

A wannan babi, hydroxypropyl methylcellulose har yanzu ana amfani dashi azaman albarkatun ƙasa, da kuma fim mai narkewa ruwa mai narkewa ta hanyar hanyar samar da mafita fim. , Elongation a hutu), kaddarorin popongica (transrittance, haze) da kuma karancin ruwa.

3.2 Ma'aikatar Gwaji

3.2.1 Abubuwan gwaji da kayan aiki

Tebur 3.1 Abubuwan gwaji da bayanai dalla-dalla

Table 3.2 Kayan Gwaji da Bayani

3.2.2 Samfiri Samfuri

1) Yin nauyi: hydroxypyl yadudduka

2) Ruwadi: ƙara yadudduka hydroxypyl methyplulopyl methylcelose a cikin ruwa da aka shirya, sannan ƙara glycerol ko matsin lamba a cikin gratitol daban-daban gundura bi da bi. A cikin Hydroxypyl methylcellulopyl methylcellulo bayani bayani, dama na tsawon lokaci don sanya shi a ko'ina, kuma bari ya gauraya minti 5 (defoaming) don samun takamaiman maida hankali ne na ruwa-forming.

3) Yin fim: Ba ​​da ruwa mai ruwa a cikin gilashin gidan abinci kuma ka jefa shi a wani fim mai bushewa da kauri 45 μm. Bayan an sanya fim a cikin akwatin bushewa don amfani.

3.2.3 hali da gwajin aiki

3.2.3.1 Infraler Sharad da Wasannin Wasan kwaikwayo (FT-Ir)

Propectrared Sharfe Proctroscopy (ftir) hanya ce mai ƙarfi don rarrabe kungiyoyin aikin da ke cikin tsarin kwayar halitta da kuma gano ƙungiyoyin aiki. An auna rubutun kwayar cutar ta HPMC na fim ɗin HPMC ta amfani da Nicolet 5700 Height Extreer canzawa infretermomer. An yi amfani da hanyar fim na bakin ciki a wannan gwajin, kewayon masu binciken ya kasance 500, kuma adadin sikeli ya bushe a cikin busasshen bushewa a 50 ° C na 24 h don m spectroscopy.

3.2.3.2 Zaɓaɓɓen-kusurwa-ray maimaitawa (XRD): Manufar 2.2.3.1

3.2.3.3.3

Ana amfani da ƙarfi da elongation da elongation a hutu na fim ɗin azaman sigogi don yanke hukunci kan kadarorin kayan aikinta. Elongation a cikin karya shine rabo na gudun hijira zuwa asalin tsawon lokacin da fim ya karye, a%. Yin amfani da Instron (5943) karamin kayan lantarki na hanyoyin gwaji na duniya (Shanghai), 50% Hanyar Rh190, zaɓi Samfuran Rana mai laushi da ƙasa mai tsabta ba tare da an gwada su ba.

3.2.3.4.4 DEARPION OFFTICALINCTIES: Man daya a 2.2.3.3

3.2.3.5 Deungiyoyin karfafa ruwa

Yanke wani 30mm × 30mm fim tare da kauri na kusan 45μm, ƙara 100ml na ruwa zuwa ga mai ruwa na 200ml, kuma auna lokacin don ɓacewa gaba daya [56]. An auna kowane samfurin sau 3 kuma an dauki matsakaicin matsakaita, kuma naúrar ta kasance min.

3.2.4 sarrafa bayanai

An sarrafa bayanan gwaji ta hanyar Excel, kuma an zana jadawalin ta hanyar software na asali.

3.3 sakamakon da tattaunawa

3.3.1 Sakamakon Glycerol da Sorbitol a cikin wasan kwaikwayo na shan taba na fina-finai na HPMC

(a) glycerol (b) Sorbitol

Fifi

Propectrared Sharfe Proctroscopy (ftir) hanya ce mai ƙarfi don rarrabe kungiyoyin aikin da ke cikin tsarin kwayar halitta da kuma gano ƙungiyoyin aiki. Hoto 3.1 yana nuna wasan kwaikwayo na HPMAC na HPMC tare da ƙari na Glycitol da ƙari. Ana iya gani daga adadi cewa halayyar mutum mai halayyar mutum na HPMAC na HPMC galibi a cikin yankuna biyu: 2600 ~ 17 da 700cm-1 [57-59], 3418CM-1

Bandungiyar shaye-shaye ta kusa da fadada ta hanyar girgiza kai na OH BOND, 2935CM-1 shine mafi girman kungiyoyin farko da na biyu, kuma 165ck-1 shine mafi girman ƙwayoyin hydroxypolyl. Kwayar cutar hydroxyl a cikin mawuyacin rawar da aka shimfiɗa na tsarin, 945cm-1 ganiya ce ta -ch3 [69]. An sanya 13, 137cM-1, 1373cm-1, 1315cm-1, 1315cm-1 da 945cm-1 da 945cm-1 da 945cm-1 da 945cm-1, bijirewa na asymmetric, cikin-jirgin sama da kuma symmetrical mawuyacin girgiza -ch3, bi da shi [18]. Bayan filastik, babu sabon kofa na ƙwaƙwalwa na ɗaukar hoto na fim, wanda ke nuna cewa hpmc bai sha bamban canje-canje ba, wato, filastik bai lalata tsarinta ba. Tare da ƙari na glycerol, babban mawuyacin rawar da ya fadi a 3418CM-1, koka na farko da kuma -Coc- a kan kungiyoyin farko da sakandare hydroxyl sun raunana; Tare da Bugu da kari na Sorbitol zuwa fim ɗin HPMC, The -Oh yana shimfiɗa koti mai tsayayye a 3418CM-1 ya raunana, da kuma ƙamshi a 1657cm-1 sun raunana. . Canje-canje na waɗannan ƙoshin wannan ƙoshin shaye-shaye ne ta hanyar rashin sakamako da haɗin hydrogen mai ban sha'awa, wanda ya sa su canza tare da maƙarƙashiya mai kyau -ch3 da -ch2 da -ch2 da -ch2 da -ch2. Saboda karami, shigar da abubuwan kwayoyin halittar da ke haifar da samuwar Hydrogen Hydrogencolencoledcolencoledcolencoledcolencolen, don karfin da ke da karfin fim din ya ragu [70].

3.3.2 Sakamakon Glycerol da Sorbitol a kan XR na XRMC Fim na HPMC

(a) glycerol (b) Sorbitol

Fig

Worl-kusurwa-kwana rarrabuwa (XRD) nazarin yanayin abubuwan da ke tattare da abubuwa a matakin kwayoyin. An yi amfani da X-Ray wanda aka samar da kamfanin kamfanin Throbo Arl a Switzerland ya yi amfani da hukuncin. Hoto 3.2 Shin ƙirar XRMC na finafinan HPMC tare da bambance-bambancen daban-daban na glycerol. Tare da Bugu da kari na glycerror, da tsanani daga cikin yaduwar kololraction a 9.5 ° da 20.4 ° duka rauni; Tare da Bugu da kari na Sorbitol, lokacin da adadin ya kasance 0.15%, ganyayyaki na raguwa a 9.5 ° ya yi rauni, amma jimlar ƙarfin haɓaka ba tare da ɗan ƙaramin fim ba. Tare da ci gaba da sorbitol, ganyen digo a 9.5 ° ya raunana kuma, da kuma girman ƙarfi a 20.4 ° bai canza sosai ba. Wannan saboda ƙari ne na ƙananan kwayoyin halittar glycerol da kuma dan wasan santsi na rikice-rikice na kwayoyin kwayoyin, don haka rage yawan fitilar fim. Ana iya gani daga adadi wanda Glycol yana da tasiri sosai a kan fina-finai na HPMAC, wanda ke nuna cewa glycent da hpmc da hpmc da hpmc da hpmc da rashin jituwa sosai. Daga tsarin bincike na filastik, sorbitol yana da tsarin zobe na sukari wanda ke da girma, da kwayoyin sarkar sa, don haka ba shi da ƙarancin tasirin cllulose.

[48].

3.3.3 Sakamakon Glycerol da Sorbitol a kan kayan aikin na HPMC

Ana amfani da ƙarfi da elongation da elongation a karya fim ɗin don yin hukunci da kadarorin aikinta, da kuma ma'aunin kayan aikin na iya yin hukunci a aikace-aikacen ta a wasu fannoni. Hoto 3.3 yana nuna canji a cikin ƙarfi na tenerilation da elongation a lokacin hutu na HPMAC bayan ƙara filastik.

Fig.3.3 Sakamakon glycerol ko Sorbitolumon akan kayan masarufi na fina-finai na HPMC

Ana iya gani daga hoto 3.3 (a) cewa tare da ƙari na Glycerol, da elongation a cikin hutu na HPMC ya fara raguwa sannan kuma yana ƙaruwa a hankali sannan ya ci gaba da raguwa. Elongation a hutu na HPMC na farko ya karu sannan ya ragu, saboda glyollol yana da abubuwa masu ruwa da kwayoyin halitta suna da tasirin hydrophilic [71], don haka inganta sassauci na fim. Tare da ci gaba da karuwar Gllycer ƙari, elongation a cikin hutu na HPMC ya ragu, wannan kuma don glycoler ya rage, ta haka ne rage elongation a cikin hutu fim. Dalilin rage girman ƙarfin ƙarfin tensile shine: ƙari da ƙananan ƙwayoyin glycolular da ke da ƙarfi tsakanin sarƙoƙin na HPRMECULE, kuma yana raunana ƙarfin fina-finai; Tufarfin tenaramin karuwa, daga hangen nesa na tsarin sarkar kwayoyin, kuma yana inganta tsarin ƙwayoyin polymer ƙara dan kadan; Koyaya, idan akwai glycerol da yawa, ana shirya sarƙoƙi da yawa a lokaci guda kamar yadda aka tsara tsari, wanda ya rage yawan tsararren fim ɗin. Tun lokacin da toughening yake yi a kashe da tenaitran karfin fim din HPMC, adadin Glycerrel Add bai yi yawa ba.

Kamar yadda aka nuna a hoto na 3.3 (b), tare da ƙari da ɗan Sorbitol, elongation a hutu na HPMC na farko ya ƙaru sannan ya ragu. Lokacin da adadin Sorbitol ya kasance kashi 0.15%, elongation a cikin hutu na HPMC ya kai 45%, sannan kuma elongation a hutu na fim a hankali ya ragu. Arfin da ke ƙasa yana raguwa da sauri, sannan kuma yana hawa kusan 50mp tare da ci gaba da ƙari na Sorbitol. Ana iya ganin hakan lokacin da adadin Sorbittol ya ƙara shine 0.15%, sakamako ne mafi kyau. Wannan saboda ƙari ne na ƙananan kwayoyin halitta na tsarin yau da kullun na kwayoyin, don haɓaka fim ɗin yana ƙaruwa da girman fim ɗin, da ƙarfin haɓaka suna ƙaruwa da ƙarfin haɓaka na haɓaka. Kamar yadda adadin Sorbitol ya ci gaba da ƙaruwa, elongation a ƙarar fim ɗin ya sake tarwatsa tsakanin Macromecolet da raguwa a cikin elongcle da raguwar elongculation a cikin hutu na fim.

Kwatanta sakamako masu illa na Glycerol da Soritol a fina-finai na HPMC, ƙara 0.15% glycerol na iya haɓaka elongation a kusan fim ɗin kusan 50%; Yayinda ƙara 0.15% Sorbitol zai iya ƙara elongation a cikin hutu na fim ɗin ya kai kusan kashi 45%. Tenarfin tenarfafa ya ragu, kuma raguwar ya karami lokacin da aka kara Glycoler. Ana iya ganin cewa Profuldar Tushen Glycerol akan fim ɗin HPMC ya fi na Sorbitol.

3.3.4 Sakamakon Glycerol da Sorbitol a kan Poptical Properties na Fina-finafin HPMC

(a) glycerol (b) Sorbitol

Fig.3.4 Sakamakon glycerol ko Sorbitolumon Sortbolumon na HPMC Fina-finai

Haske mai haske da kuma haze sune sigogi masu mahimmanci na fassarar fim ɗin cocaging. Ganuwa da kuma bayyane kayan aikin da aka shirya galibi suna dogara da hasken transmitance da haze of cocaging fim. Kamar yadda aka nuna a hoto 3.4, ƙari da glycerol da kuma dan sigbet duka ya shafi kayan popical kaddarorin finafinai na HPMC, musamman ma haze. Hoto 3.4 (a) Graph ne mai nuna tasirin tasirin glycerari akan abubuwan da kayan adon HPMC. Tare da Bugu da kari na glycerrance, watsa na HPMAC Fina-finai da farko ya karu sannan ya ragu, kai ga matsakaicin darajar kusan 0.25%; Haze ya karu da sauri sannan kuma a hankali. Ana iya gani daga bincike na sama wanda lokacin da adadin glycoler shine 0.25%, abubuwan gani na Fim ɗin sun fi kyau, don haka adadin Glycerol bai wuce kashi 0.25% ba. Hoto 3.4 (b) Graph ne mai nuna tasirin Sorbitol Bugu da kari akan abubuwan da kayan gani na fina-finai na HPMC. Ana iya ganin hakan daga adon wanda tare da ƙari da kayan masarufi, haze of hpmC finafinai yana ƙaruwa, sannan yana ƙaruwa, kuma yana ƙaruwa, kuma yana ƙaruwa, kuma yana ƙaruwa, kuma yana ƙaruwa da yawa sannan kuma yana ƙaruwa. Rushewa, da hasken transritance da haee bayyana kololuwa a lokaci guda lokacin da adadin Sorbitol ya 0.45%. Ana iya ganin cewa lokacin da adadin Sorbittol ya ƙara tsakanin 0.35 da 0.45%, poptical kaddarorin sun fi kyau. Kwatanta sakamakon Glycerol da Sorbitol a kan popical kaddarorin finafinan fina-finai, ana iya ganin cewa sorbitol bashi da kadan tasiri a kan popical kaddarorin.

Gabaɗaya magana, kayan tare da babban haske watsa watsa kai zasu sami ƙananan hae, da kuma mataimakin men, amma wannan ba koyaushe yake ba. Wasu kayan suna da babban haske Trmittance amma kuma maɗaurin Haze Haze, irin su fina-finai kamar gilashin bushewa [73]. Figurin da aka shirya a wannan gwajin na iya zabi mai filastik da ya dace da adadin da ya dace gwargwadon bukatun.

3.3.5 sakamakon glycerol da dan sigbetol a kan karfin ruwa na fina-finai na HPMC

(a) glycerol (b) Sorbitol

Siffa

Hoto 3.5 yana nuna sakamakon glycerol da kuma santsi a kan ruwa donli na fina-finai na HPMC. Ana iya ganinsa daga adadi wanda tare da karuwar abun cikin filastik, ruwan sha na fim ɗin HPMC ya ragu sosai, da Glycerol yana da babban tasiri a kan solubility na HPMC fiye da Sorbitol. Dalilin da ya sa Hydroxypoyl methylcellilyl methylcellilyl methylellulose yana da kyau donli na ruwa shine saboda kasancewar adadi mai yawa na ƙungiyoyi na hydroxyl a cikin kwayar sa. Daga nazarin tsokanar da aka harba, ana iya ganin cewa tare da ƙari na glycomol, wanda ke nuna cewa yawan ƙwayoyin Hydroxhilic ya ragu, don haka ƙarfin ruwan hepmc yana raguwa.

3.4 sassan wannan babi

Ta hanyar bincike na na sama na sama na hpmC, ana iya ganin cewa filastik Glycerrs da Sorbitol yana inganta kayan aikin kayan finafinan hpmc da ƙara elongation a cikin fina-finai. Lokacin da ƙari da Glycerol shine 0.15%, kaddarorin na kayan aikin HPMAC suna da kyau, ƙarfin tenscsa shine kusan kashi 50%; Lokacin da Bugu da kari na glycerol shine 0.25%, da abubuwan gani sun fi kyau. Lokacin da abun ciki na Sorbitol shine 0.15%, ƙarfin haɓaka fim ne kusan 55ppta, kuma elongation a cikin karya yana ƙaruwa kusan kashi 45%. Lokacin da abun cikin Sorbitol shine 0.45%, da abubuwan gani na fim ɗin sun fi kyau. Dukansu filastik sun rage yawan fina-finai na HPMC, yayin da Sorbitol ba shi da tasiri a kan kayan aikin ruwa na HPMC. Kwatancen sakamakon tasirin filastik biyu a kan kadarorin finafinai na HPMC ya nuna cewa an samar da sakamakon filayen Glycer.

Babi na 4 sakamakon wakilai na masu fasahar ruwa a fina-finai mai narkewa

4.1 Gabatarwa

Hydroxypyl methcelcele ya ƙunshi ƙungiyoyi masu yawa na hydroxyl da kuma hydroxypropoxoxoxy, don haka yana da kyakkyawan abinci na ruwa. Wannan takarda tana amfani da kyakkyawan ruwa na ruwa don shirya sabon labari na green da kuma fim mai amfani da ruwa mai amfani da ruwa mai amfani. Ya danganta da aikace-aikacen fim mai narkewa, rarrabuwar fim ɗin ana buƙatar fim mai narkewa a cikin yawancin aikace-aikacen ruwa, amma wani lokacin an jinkirta rushewa ana so [21].

Saboda haka, a cikin wannan babi, ana amfani da glutalaldehyde a matsayin mai haɗa wakilin haɗin ruwa na ruwa mai narkewa na ruwa don rage yawan fim ɗin da jinkirtar da lokacin karancin ruwa. Sakamakon tasirin girma na glutaralde a kan ruwa na ruwa, kaddarorin na kayan aiki da abubuwan pictical pictripropyl methylcellullopyl methylcellillopyl aka yi nazari sosai.

4.2 na gwaji

4.2.1 Abubuwan gwaji da kayan aiki

Table 4.1 Abubuwan gwaji da bayanai dalla-dalla

4.2.2 Fantaliten shiri

1) Yin nauyi: auna wani adadin hydroxypropyl methylcellulopyl methylcellulose (5%) tare da ma'auni na lantarki;

2) rushewa: An haɗa hydroxypyl methylcellose da aka shirya (0.19%), 0.38% na ruwa mai yawa, da ruwa daban-daban, da kuma ruwa-facting ruwa tare da daban-daban An samo adadin Glutaraldehdeh;

3) Yin fim: Ba ​​da fim ɗin da ke haifar da ruwa mai ruwa a cikin gilashin bushewa, sanya fim ɗin da keyren iska, ya kuma sanya shi a cikin akwatin bushewa don Ajiyayyen.

4.2.3 hali da gwajin aikin

4.2.3.1 Infraler Sharad da Spectroscopy (FT-Ir)

An ƙuntata tsotsa na hpmC fina-finai da aka ƙaddara ta amfani da Nicolet 5700 Height Exter enmometer na Amurka wanda ke samar da batun kamfanin da Ba'amurke Ba'amurke ya fitar kusa da Kamfanin kamfanin Amurka.

4.2.3.2 X-kwana-obsroproctions (xrd) bincike

Zazzabi mai tsayi-kwana (XRD) shine bincike game da yanayin crystallization na wani abu a matakin kwayoyin. A cikin wannan takarda, yanayin crystallization na fim an ƙaddara shi ta amfani da Arl / Xtra X-ray Ischractometomer wanda aka samar ta hanyar Thermo Ar Switzerland. Yanayin ma'auni: tushen X-ray shine layin CU-KV na layi (40 KV, 40 Ma). Duba kwana daga 0 ° zuwa 80 ° (2θ). Scan sauri 6 ° / min.

4.2.3.3 REYUWAR RUWAN RUHU: iri ɗaya ne kamar 2.2.3.4

4.2.3.4

Yin amfani da Instron (5943) Makarantar Kayan Kayan Gida na duniya (Shanghai), 50% Hanyar GB130-92 don an gwada su.

4.2.3.5 Dearfafa Ka'idodin Kayan Kayan Hoto

Ta amfani da haske transtritance Haze Tester, zaɓi samfurin za a gwada tare da tsaftataccen yanayin da hazalin fim ɗin a ɗakin zazzabi (25 ° C da 50% RR).

4.2.4 sarrafa bayanai

An aiwatar da bayanan gwaji da Excelerce kuma an yi nasara da kayan aikin asali.

Sakamako na 4.3 da tattaunawa

4.3.1 Infrared Spectra na karin haske-Crossanked HPMAC Fina-Finan

Fig

Spectroscopy foctroscopy foctroscopy yana da karfi wajen nuna ma'anar ayyukan aikin da ke cikin tsari na kwayar halitta da kuma gano ƙungiyoyin aiki. Don kara fahimtar yanayin tsarin hydroxypropyl methylcelllilulin bayan gyara, an gudanar da gwaje-gwaje a kan fina-finai a da bayan canji. Hoto 4.1 yana nuna wasan kwaikwayo na HPMC tare da adadin da yawa na glutaralde, da kuma nakasar fina-finai na HPMC

Tsayinfin tsattsauran ra'ayi na -oh suna kusa da 3418cm-1 da 1657cm-1. Kwatanta da Crossanked da kuma ba'a tantancewa ba na fina-finai na HPMAC ba, ana iya ganin hakan tare da ƙari ga grinroxypholefoxoxy ya raunana, yana nuna cewa yawan ƙungiyoyin hydroxyl. A cikin kwayar cutar HPMC ta rage, wanda aka haifar da shi ta hanyar hada-hadar da ke haifar da shi tsakanin wasu kungiyoyin Hydroxyl na HPMC da kuma kungiyar da ba ta dace ba a kan Glutaraldealdealdehyde [74]. Bugu da kari, an gano cewa ƙari na Glutanaldehyde bai canza matsayin kowane hali na HPMC na HPMC ba, yana nuna cewa ƙarin ƙari na HPMC kansa.

4.3.2 alamomin XD.2 na Glutaraldehyde-Crossanked HPMC Fina-finai

Ta hanyar yin digo na X-ray akan kayan da kuma nazarin tsarin saɓɓin sa, hanya ce ta bincike don samun bayanai kamar tsari ko kwayoyin halitta na atoms ko kwayoyin halitta a cikin kayan. Hoto 4.2 yana nuna tsarin da aka zana na fina-finai na HPMC tare da grutaralde ƙari. Tare da karuwar glutaralde ƙari, tsananin yaduwar kolaye na HPMC a kusa da 9.5 ° da 20.4 ° ya raunana, saboda da aka raunana a kan grutaraldeed. Haɗin haɗin haɗawa yana faruwa ne tsakanin ƙungiyar Hydroxyl da ƙungiyar Hydroxyl a kan kwayoyin HPMC, wanda ke iyakance ikon sarkar kwayoyin halitta [75], don haka yana rage yawan tsarin kwayar cutar HPMC.

Fig.4.2 Xd na fina-finai na HPMC a karkashin abun cikin Glutaraldedede

4.3.3 Sakamakon glutaralde a kan kayan aikin ruwa na HPMC

Fig.4.3 Sakamakon glutaralde a kan ruwa na ruwa na fina-finai na HPMC

Daga Hoto 4.3 Sakamakon daban-daban glutaraldeitiesari akan ruwa donli na HPMAC na HPMC, ana iya ganin cewa tare da karuwar sashi na glutaraldde, ruwan sha na hpmC fina-finai yana tsawan lokaci. Haɗin haɗi na baya yana faruwa tare da ƙungiyar ABINDDE akan Glutaraldehydehyde, wanda ya haifar da raguwa a cikin adadin kayan HPMC da kuma rage yawan samar da ruwa na fim ɗin HPMC.

4.3.4 Sakamakon Glutanaldehyde akan kayan aikin injin na HPMC

Fit

Don bincika tasirin abun ciki na glutaraldede akan kayan aikin hpmc, an gwada ƙarfin ƙarfi a cikin hutu na kayan kwalliya. Misali, 4.4 shine jadawalin tasirin glotaralde ƙari a kan ƙarfin ƙarfin da elongation a hutu na fim. Tare da karuwar glutaralde ƙari, tenarfafa tenal da elongation a hutu na HPMC ya karu da farko sannan kuma ya ragu. da trend na. Tunda hanyoyin haɗin gwiwar glutaralde da selullose na hanyar gaggafa da kungiyoyin HPMC, da ke da ƙungiyoyin hanyoyin haɗi don samar da kayan haɗin ether. Tare da ci gaba da ƙari na glutaraldehyde, haɗarin haɗin kai a cikin mafita na haɓaka, wanda ya nuna cewa kayan aikin ƙasa na ɓoyayyen hpmc ƙi macroscopally [76]. Daga Hoto 4.4, sakamakon glutaraldealdehyde a kan kayan aikin na HPMC na nuna cewa lokacin da ƙari na kayan aikin HPMC sun fi kyau.

4.3.5 Sakamakon glutaralde a kan abubuwan da kayan aikin HPMC

Haske mai haske da kuma haze sune mahimman sigogin wasan kwaikwayon na pictuling na fina-finai. Mafi girma daga cikin transtance, mafi kyawun kalmar fina-finai; Haze, wanda kuma aka sani da turbi na, yana nuna digiri na Innisinciness na fim, da mafi girma Haze, mafi muni a bayyane na fim. Hoto 4.5 shine tasirin tasiri na ƙari na glutaraldehyde a kan abubuwan da na gani na kayan finafinan hpmc. Ana iya ganinsa daga adadi wanda tare da karuwar ƙari na ƙari na Glutaralde, to, yana ƙaruwa a hankali sannan kuma yana raguwa a hankali; Haze shi da farko ya ragu sannan ya karu. Lokacin da Bugu da kari na Glutaraldeh ne 0.25%, watsa na fim din HPMC ya kai iyakar darajar kashi 93%, kuma heze ya isa mafi karancin darajar 13%. A wannan lokacin, da hangen ne ya yi kyau. Dalilin karuwa a cikin kayan pictical kaddaruwa shine hadar da kwayoyin halitta tsakanin glutaraldeplulose, da kuma tsarin hayaki yana ƙaruwa da kayan aikin hpmc [77-79]. Lokacin da wakilin haɗin haɗi na giciye ya wuce kima, shafukan haɗarin haɗin yanar gizon suna da matsala tsakanin kwayoyin halitta na tsarin yana da wahala, kuma mai ɗaukar hoto yana da sauƙi a faruwa. Sabili da haka, abubuwan da abubuwan gani na finafinan HPMC sun rage [80].

Fig.4.5 Sakamakon Glutaraldehyde a kan kayan pictical na fina-finai na HPMC

4.4 sassan wannan babi

Ta hanyar bincike na sama, waɗannan da aka zaba ana jawo su:

1) Spectrum spectrum na daɗaɗɗen fim ɗin HPMAC ya nuna cewa glutaraldealde da fim ɗin HPMC suna fuskantar hanyar haɗin haɗi.

2) ya fi dacewa don ƙara glutaraldehyde a cikin kewayon 0.25% zuwa 0.44%. Lokacin da adadin adadin Glutaraldehyde shine 0.25%, da cikakkiyar kayan aikin da na optical na fim ɗin HPMC sun fi kyau; Bayan haɗin haɗi, ruwan sha na samar da fim ɗin HPMC yana tsawan lokaci kuma ana rage karfin ruwa. Lokacin da ƙwararrawar adadin glutaraldehyde 0.44%, lokacin ƙwadun ruwa kai game da 135min.

Fasali na 5 na halitta antioxidant hpmc ruwa mai narkewa

5.1 Gabatarwa

Don faɗaɗa aikace-aikacen hydroxypropyl methylcellulopyl methylellose fim a cikin farfado na abinci antioxidant (AB babi na maganin antioxidants na asali. Fim na antioxidant hpmc ruwa mai narkewa, nazarin kayan aikin antioxidant, kayan ruwa na ruwa da kayan aikin injin, kuma ba da tushen aikin saiti na abinci.

5.2 Kashi na Gwaji

5.2.1 Abubuwan gwaji da kayan abinci na gwaji

Tab.5.1 Abubuwan gwaji da bayanai dalla-dalla

Tab.59.2 Gwaji Tallafi da Bayani

5.2.2 Abubuwan samfuri

Shirya hydroxypyl methylcel fenara ruwa mai narkewa mai ruwa mai narkewa tare da nau'in casting na maganin antitetly, sannan, 0.01%, 0.05%, 0.05%, 0.05%, 0.07%, 0.09%) na fure fure antitidants zuwa ga sel-samar da bayani-ƙirƙirar bayani, kuma ci gaba da motsa jiki

Don a haɗe sosai, bari a tsaya a zazzabi a daki na mintina 3-5 (wanda ya sa) ƙirƙirar ƙananan ƙananan fim ɗin da ke ɗauke da ƙirar taro daban-daban na ganye na fure. Dry shi a cikin bushewa na fashewa, kuma sanya shi a cikin bushewar bushewa don amfani bayan amfani bayan amfani da fim. Theyy hydroxypyl methylcellulopyl methylcele ruwa mai narkewa ruwa AntioxiDant ana magana ne a matsayin AOB / HPMC na takaice.

5.2.3 hali da gwajin aiki

5.3.1 Infrostcopy ftuctroscopy (ft-Ir)

An auna Pubcra na HPRC na HPRC na HPRC na HPRC a cikin yanayin atr ta amfani da Nicolet 5700 Heerier canzawa ta haifar da Spectrometer mai ban sha'awa.

5.2.3.2 Bambancin X-Rabzanci (XRD) aunawa: iri ɗaya kamar 2.2.3.1

5.2.3.3 Dogara ta maganin antioxidant

Don auna kaddarorin antioxidant na fina-finai da aka shirya HPMC da AOB / HPMC kyauta, ana amfani da hanyar Schidaddamar da fina-finai don auna ƙwayar iskar shaka-tsattsauran ra'ayi, don haka don auna ƙwayar iskar shaka-fina-finai.

Shiri na maganin DPPHh: A cikin yanayin shading, narke 2 na DPPH a cikin 40 ml na sauran ƙarfi, da sonicate na mintuna 5 don yin suturar maganin. Adana a cikin firiji (4 ° C) don amfani ta gaba.

Magana game da hanyar gwaji na Zhong Yuansgeng [81], tare da karamin canji, darajar ruwa a cikin tubalin gwaji, sannan a auna darajar DPPH. shine0. A gwada darajar: ƙara 2 ml na maganin dPPH don warware ƙwayar fim, sannan a yi amfani da darajar abin da ba komai. DPPH kyauta mai narkewa mai narkewa mai narkewa yana nufin tsari mai zuwa,

A cikin dabara: a shine shayar da samfurin; A0 shine matsalar ba komai

5.2.3.4 DEFEFT Deeiyya kadai: Man daya a matsayin 2.2.3.2

5..2.3.5 Deungiyoyin ƙuduri na Officies

Abubuwan da ke cikin tsari sune mahimman alamu na bayyanannun fina-finai, akasarinsu har da transmitance da haze na fim. A juyawa da kuma haze of fina-finai an auna ta amfani da transttance Haze Tester. Haske na watsa haske da haze of fina-finai an auna a zazzabi a daki (25 ° C da 50% RH) akan samfuran gwaji tare da tsabtatu kuma babu creases.

5.2.3.6 don tabbatar da kariyar ruwa

Yanke wani 30mm × 30mm fim tare da kauri na kimanin 45μm, ƙara 100ml na ruwa zuwa ga mai ruwa na 200ml, kuma auna lokacin fim don bace gaba daya. Idan fim ɗin ya tsaya a bango na beaker, yana buƙatar sake auna shi, kuma ana ɗaukar sakamakon kamar matsakaita na sau 3, rukunin yana min.

5.2.4 sarrafa bayanai

An aiwatar da bayanan gwaji da Excelerce kuma an yi nasara da kayan aikin asali.

5.3 sakamakon da bincike

5.3.1 Binciken Ft-Ir

Fig5.1 Ftir na HPMC da AOB / HPMC Fina-finai

A cikin kwayoyin halitta, kwayoyin halitta waɗanda ke haifar da haɗin sunadarai ko ƙungiyoyin aiki suna cikin yanayin rawar jiki. Lokacin da kwayoyin halitta ke farfadowa da hasken wuta, bangarorin sunadarai ko kungiyoyin aiki a cikin manyan kwayoyin za su iya sha. Hoto 5.1 ya nuna wasan ftir na fim din HPMC da AOB / HPMC. Daga Hoto na 5, ana iya ganin cewa halayyar rasuwar mai saki na methyllulopoyl methylcellulose yafi mai da hankali cikin 26 da 750 ~ 1700 cm-1. Matsakaicin tsananin matsanancin iska a cikin yankin 950-1250 cm-1 shine mafi yawan halayyar yankin co sreleton shimfiɗa rawar da ke shimfiɗawa. Kwandun na fim na HPMC na kusa da 3418 cm-1 shine sakamakon girgiza hydroxyp on 1657 cm-1 ne sakamakon girgiza kai na tsarin [82]. Cire na sha a 1454cm-1, 1373cm-1, 1315cm-1 da 945cm-1 da 945cm-1 da 945cm-1 da 945cm-1, a cikin jirgin sama da kuma symmetrical vibrations mallakar -Ch3 [83]. An gyara HPMC da AOB. Tare da Bugu da kari na AOB, matsayin kowane hali na kowane hali na AOB / HPMC bai matsa masa ba, yana nuna cewa ƙarin ƙari na HPMC da kansa bai lalata gungun da kanta ba. Rufancin rawar da ke addanger a cikin sha na AOB / HPMC Fim kusa da 3418 cm-1 ne yafi lalacewa saboda canjin metilent methyl da methylene Bands saboda canjin Hydrencent. 12], za a iya ganin cewa Bugu da ƙari AB yana da tasiri akan shaidu na hydrolencular.

Tsarin Bincike 5.3.2.2

Fig.52 XRd na HPMC da AOB /

Fig.59 XRd na HPMC da AOB / HPMC Fina-finai

An bincika yanayin crystallo na fina-finai ta hanyar ɗakunan-kusurwa mai kunnawa. Hoto na 52 yana nuna alamun launin finafinan HPMAC da Fina-finai AAOT / HPMAC. Ana iya ganin shi daga adadi cewa fim ɗin HPMC yana da kololuwa 2 naƙasasshe (9.5 °, 20.4 °). Tare da Bugu da kari na AOB, wanda ya musanya koli a kusa da 9.5 ° da 20.4 ° yana da rauni sosai, ana nuna cewa an tsara kwayoyin a cikin tsari na AOB / HPMC. Ikon ya ragu, yana nuna cewa Bugu da kari da ƙari na ƙwayar ƙwayar cuta, kuma ya rage tsarin yau da kullun na hydroxypropyl methylcellulhopyl methylcellulpoyl methylcellullopyl methylcellullopyl methylcelypoyl

5.3.3 Abubuwan Antioxidant

Don bincika tasirin tasirin AB daban-daban game da iskar shaka daban-daban na AOB / HPMC fina-finai, 0.03%, 0.03%, 0.05%, 0.05%) an bincika 0.03%) an bincika 0.03%) an bincika 0.03%) Tasirin raguwar bagade, an nuna sakamakon a cikin Hoto na 5.3.

Fig.5.3 Sakamakon finafinan HPMAC a ƙarƙashin abun ciki na Aob akan DPPH PHABID

Ana iya ganin hakan daga Hoto 5.3 cewa ƙarin AEB antioxidant muhimmanci sosai ragin fina-finai da aka inganta, kuma tare da karuwar kayan ado na farko, kuma tare da karuwar kayan kwalliya da farko ya ragu. Lokacin da adadin Aob shine 0.03%, fim ɗin AB / HPMC yana da mafi kyawun sakamako na DPPH / HPMC yana da mafi kyawun aikin haushi a wannan lokacin; Lokacin da abun ciki na AB ya kasance 0.05% da 0.07%, DPPH kyauta mai tsattsauran ra'ayi na AOB / HPMC ya fi ta rukuni na 0.01%, amma yana da ƙasa da na 0.03% rukuni; Wannan na iya zama saboda wuce gona da iri na halitta wanda akayi wani karin gishiri da aka haifar da tashin hankali na kwayoyin, da kuma rarraba abubuwa a cikin fim, hpmc fina-finai. Ana iya ganin cewa fim / HPMC da aka shirya a cikin gwajin yana da kyakkyawan aikin oxidation. Lokacin da adadin yake 0.03%, aikin oxidation oad da oxidation na AOB / HPMC shine mafi ƙarfi.

5.3.4 Ruwa na Ruwa

Daga Hoto 5.4, sakamakon bambaro ganye antioxidants a kan ruwa donli na hydroxypillopyl methylcellulo fina-finai, ana iya ganin cewa banbancin AB. Bayan ƙara AOB, tare da karuwar adadin AOB, lokacin da lokacin ruwa mai narkewa na fim ɗin ya ga gajarta, yana nuna cewa ruwa-fim ɗin HPMC ya fi kyau. Wato ,addiyar aiob inganta AB / HPMC ruwa don ƙarin fim. Daga nazarin XD na baya, ana iya ganin cewa bayan ƙara Aob, an rage yawan ƙwayoyin ruwa don shigar da fim ɗin AOB, wanda ya sa ya shigar da fim ɗin AOB, wanda ya inganta tsakanin sarƙoƙin AOB, wanda ya inganta a tsakanin sarƙoƙin Aob / HPMC ya inganta zuwa wani lokaci. Solubility na ruwa na fim.

Fig.5.4 Sakamakon AOB akan ruwa mai narkewa na fina-finai na HPMC

5.3.5 kaddarorin inji

Fig.5.5 sakamakon AOB akan ƙarfi da kuma karya elongation na fim ɗin HPMC

Aikace-aikacen kayan fim na bakin ciki yafi da yawa, kuma kayan aikin injin din suna da babban tasiri a tsarin sabis na membrane, wanda ya zama babban bincike na membrane. Hoto na 5.5 yana nuna karfin da elongation da elongation a karya da fina-finai na AOB / HPMC. Ana iya ganinsa daga adadi wanda tartsasan AOB daban-daban suna da tasiri sosai akan kayan aikin na fina-finai. Bayan ƙara Aob, tare da karuwar Aob Bugu da kari, AOB / HPMC. Thearfin fim ɗin ya nuna alamar ƙasa, yayin da elongation a karya ya nuna yanayin farkon karuwa kuma ya ragewa. Lokacin da abun ciki na AB ya kasance 0.01%, elongation a hutu na fim ya kai matsakaicin darajar kimanin 45%. Tasirin AOB a kan kayan aikin na HPMC a bayyane yake. Daga bincike na XRD, ana iya ganin cewa ABDIOXIDAT ABUOXIDATTTTTTTATIYATINDINITY AOB / HPMC, ta rage yawan ƙarfin fina-finai na AOB / HPMC. Elongation a karya farko yana ƙaruwa sannan kuma yana raguwa, saboda AB yana da ingantaccen kayan aiki da daidaituwa, kuma ƙaramin abu ne na ƙwayoyin cuta. Yayin aiwatar da karfinsu tare da HPMC, hulɗa da karfi tsakanin kwayoyin kwayoyin suna raunana kuma fim ɗin yana da laushi. Tsarin tsayayyen yana sanya AB / HPMAC taushi mai taushi da elongation a lokacin hutu na fim; Kamar yadda AOB ya ci gaba da karuwa, da elongation a cikin fim din AOB / HPMC ya ragu, kuma babu mai shiga tsakani a tsakanin fim din AOB / HPMICHICHICHICKET, domin elongc fim ta raguwa.

5.3.6 Pictionfies Opticly

FIG.5.6 Sakamakon AOB akan mallakar kayan aikin HPMC

Hoto 5.6 Groto ne mai nuna canji a cikin transwtance da haze of AOB / hpmc fina-finai. Ana iya ganinsa daga adadi wanda tare da karuwar adadin AOB da aka ƙara, watsa gurbin AB / HPMC ya ragu kuma ƙiren yana ƙaruwa. Lokacin da abun ciki na AOB bai wuce 0.05% ba, farashin canji mai haske da haze na fina-finai na AOB / HPMC sun yi jinkirin; Lokacin da Aob abun ciki ya wuce 0.05%, farashin canji na watsa haske da haze an kara hanzarta. Saboda haka, adadin AOB ya ƙara kada ya wuce 0.05%.

5.4 sassan sassan wannan babi

Shan fure ganye antioxidant (AOB) kamar yadda antioxipyl na zahiri methylluluse (HPMC) kamar yadda matrix na fim, an shirya wani matrix na fim da aka shirya. AB / hpmc ruwa mai narkewa-mai narkewa-slabba wanda aka shirya a wannan gwajin yana da kaddarorin outsiyar outsationation. Filin AOB / HPMC tare da 0.03% AOB yana da ƙimar kimanin kashi 89% don Ingantaccen Radich Free, wanda ya fi wannan ba tare da AOB ba. Fim din HPMC a 61% inganta. Hakanan ana inganta ƙarfin ruwa sosai, kuma kayan aikin na na inji da kayan pictical sun ragu. Abubuwan da suka dace da isasshen abu ɗaya na kayan maye / kayan fim na HPMC sun fadada aikace-aikacen sa a cikin marufi abinci.

Fasali VI GWAMNATI

1) Tare da karuwar fim na HPMAC-forming bayani bayani, kaddarorin na inji na fim ɗin farko ya karu sannan ya ragu. Lokacin da HPMC fim-kirkirar bayani bayani shine 5%, kaddarorin na inji na HPMC Fim sun fi kyau, kuma karfin daukaka ya kasance 116mpa 116mpsa ya kasance 116mpta. Elongation a karya kusan 31%; da abubuwan gani da rage ruwa.

2) Tare da karuwar fim ɗin forming zazzabi, kaddarorin na inji na finafinan farko sannan ya ragu, da poptical kaddarorin ya inganta. Lokacin da zazzabi-forming zazzabi ne 50 ° C, aikin haɓaka shine kusan 110Me, don haka zazzabi mai ruwa ne mafi girma a 50 ° C.

3) Amfani da filastik don inganta ta tauri fina-finai, tare da ƙari na glycation, da elongation a hutu na HPMC ya karu sosai, yayin da karfin da ke ƙasa ya ragu. Lokacin da adadin Glycerritt ya kara da cewa tsakanin 0.15% da 0.25%, elongation a cikin hpmc fim kusan kashi 50% ne, kuma karfin da ke cikin shekaru 60 ne kusan 60m.

4) Tare da Bugu da kari na Sorbitol, elongation a hutu na fim ya fara farko sannan ya ragu. Lokacin da Bugu da lokacin da Sorbitol kusan 0.15%, elongation a cikin karya ya kai 45% da ƙarfin tensage shine kusan 55pta.

5) Additionarin Bugu da kari filastik biyu, glycerol da sorbitol, duka sun rage kayan popical da kayan ruwa na hpmc fina-finai, da raguwar ba mai girma ba. Kwatanta sakamako na filastik na filastik biyu a fina-finai biyu a fina-finai na HPMC, ana iya ganin cewa Proffolitarfin sakamako na Glycerol ya fi na Sorbitol.

6) Ta hanyar shan karin shawomare (ftir) da bincike mai fadi-bayan x-ray, hadoshin haɗawa na glutaraldealdealdealfhyde da hpmc da kuma hpmc da lu'ulu'u da lu'ulu'u da aka yi nazari. Tare da ƙari da wakilin haɗin haɗi na giciye, ƙarfin tens da elongation a hutu na kayan haɗin HPMAC da farko ya ƙaru sannan ya ragu. Lokacin da ƙari da ƙari na Glutaralde shine 0.25%, da cikakkiyar kaddarorin kayan aikin HPMC sun fi kyau; Bayan haɗin haɗi, lokaci mai narkewa yana tsawan lokaci, kuma yana raguwa da ruwa. Lokacin da ƙari da ƙari na Glutaralde shine 0.44%, lokacin ƙwadago ya kai kimanin 135min.

7 )ara adadin antioxidanant na zahiri na antioxidant zuwa ingantaccen bayani na HPMC, an shirya ABUD AOB / hpmc ruwa mai narkewa yana da kayan aikin outsiyar oxidation. Filin AOB / HPMC tare da 0.03% AOB ya ƙara 0.03% ABTGic zuwa ga kashi 89%, wanda shine 61% sama da wannan fim ɗin HPMC ba tare da Aob ba. Hakanan ana inganta ƙarfin ruwa sosai, kuma kayan aikin na na inji da kayan pictical sun ragu. Lokacin da adadin adadin 0.03% AOB, tasirin tasayen kayan shaye-shaye na fim / HPMC filaye yana faɗaɗa aikace-aikacen wannan kayan fim a cikin kayan fim.