Menene darajar pH na HPMC?

Darajar pH na HPMC (Hydroxypropyl methylcelrose) ya dogara da maida hankali a cikin mafita, zazzabi, da ingancin da tsarkakakken ruwan. Yawanci, darajar pH na HPMC a cikin bayani mai ruwa shine tsakanin 5.0 zuwa 8.0, gwargwadon yanayin rushewa da ƙayyadaddun ƙayyadaddun da masana'anta da masana'anta ke bayarwa.

1. Kayayyakin asali na HPMC
HPMC shine sel mai kyau ba mai narkewa ba a cikin magunguna, abinci da masana'antu, tare da kyakkyawan fim-forming, thickening da kwanciyar hankali. Ba-ionic ba ne, narkewa a cikin ruwan sanyi amma ba cikin ruwan zafi ba amma ba a cikin ruwan zafi ba, kuma mafita gaba ɗaya tsaka tsaki ne ko dan acidic. A cikin aikace-aikacen masana'antu, ana maraba da HPMC sosai saboda amincinsa kuma in munana tsayayyen kaddarorin.

2. PH kewayon maganin hpmc ruwa
A cewar bayanan gwaje-gwaje da adabi na wallafe-wallafe, da ph na HPMC a cikin mafi ƙarancin ƙarfi (kamar 1-2%) gaba ɗaya tsakanin 5.0 zuwa 8.0. Umarnin Samfurin da masana'anta ke bayarwa yawanci suna ba da irin mai amfani ga masu amfani don komawa zuwa lokacin tsarin saiti. Misali, darajar pH na wasu samfuran HPMC a cikin bayani 0.1% na ruwa kusan 5.5 zuwa 7.5, wanda yake kusa da tsaka tsaki.

Karancin bayani: A karancin maida hankali (<2%), darajar ph na HPMC bayan narkewa cikin ruwa yana kusa da tsaka tsaki.

Babban bayani na taro: A mafi girma maida hankali, ingancin bayani yana ƙaruwa, amma har yanzu darajar pH har yanzu yana canzawa a cikin kewayon kusa da tsaka tsaki.

Tasirin zazzabi: Solubility na HPMC ya shafi yawan zafin jiki sosai. Yana da sauƙin narkewa a cikin ruwan sanyi kuma a sauƙaƙe precipated a cikin ruwan zafin jiki na babban zazzabi. Lokacin shirya maganin HPMC, yawanci ana ba da shawarar yin amfani da ruwan sanyi don gujewa canje-canje masu narkewa da aka haifar da babban zafin jiki sosai.

3. Gano ganowa da abubuwan m
Yawancin lokaci, a lokacin samarwa da amfani, lokacin gano darajar maganin pH na maganin hpmc mai ruwa, ana amfani da mita PH don auna kai tsaye. Koyaya, waɗannan dalilai na iya shafar sakamakon ma'auni:

Tsohon ruwa: Ruwa daga kafofin daban-daban na iya ƙunsar silsolved gishiri, ma'adanai, da sauransu, wanda ke shafar sakamakon sukar. An ba da shawarar gabaɗaya don amfani da ruwan da aka narke ko ruwa mai narkewa don shirya maganin HPMC don tabbatar da daidaito na sakamakon.
Magani na bayani: mafi girma HPMC maida hankali, wanda ya fi dacewa da wasu matsaloli game da ma'aunin PH, ana amfani da karfin gwiwa (<2%) ana amfani da mafita.
Yanayin waje: zazzabi, daidaituwa na auna kayan aiki, da sauransu. Zai iya haifar da ƙananan ƙwayoyin PH.

4. Bukatun FH a cikin aikin aikace-aikacen HPMC
Lokacin da ake amfani da HPMC a cikin abinci da magani, kwanciyar hankali da kuma daidaituwar ph pho bukatar a yi la'akari. Misali, a cikin allunan pharmaceutical da shirye-shiryen capsulle, ana amfani da HPMC a matsayin zakara da kuma samar da saki da kayan saki da kuma yanayin saki da kuma lafiyar sinadari muhimmin la'akari ne. Yawancin magunguna suna buƙatar saki a cikin tsaka-tsaki ko kuma dan kadan acidic muhalli, don haka halayen ph na HPMC sun dace sosai da wannan dalili.

Masana'antar abinci: Lokacin da ake amfani da HPMC azaman Thickener, yawanci ana fatan cewa ƙimar ta pH yana kusa da tsaka tsaki don kada ya shafi ɗanɗano da kwanciyar hankali na samfurin.
Masana'antar masana'antu: A cikin Allunan da capsules, ana amfani da HPMC don sarrafa sakin magani, da kuma tsayayyen ph kusa da tsaka tsaki yana taimakawa wajen kula da ayyukan miyagun ƙwayoyi.

5. Hanyar daidaitawa na pH na maganin hpmc ruwa mai ruwa
Idan an canza darajar anti na maganin HPMC a cikin takamaiman aikace-aikacen, ana iya samun lafiya-da aka kunna ta ƙara acid ko alkali. Misali, karamin adadin tsararren hydrochloric acid ko sodium hydroxi an iya amfani dashi, amma dole ne a kula da shi a hankali don kauce wa rikicewar aminci ko kuma ya shafi kwanciyar hankali na HPMC.

Darajar pH na HPMC a cikin mafiumancin bayani gabaɗaya tsakanin 5.0 zuwa 8.0, wanda yake kusa da tsaka tsaki. Abubuwan da ake buƙata na PH na iya bambanta daban-daban aikace daban-daban na iya bambanta dan kadan, amma yawanci babu ake buƙata na musamman.