Bari mu magana game da hydroxypropyl methyl cellulose HPMC da kuma yadda za a auna ta danko.Danko a nan yana nufin danko na fili, wanda shine muhimmin magana ga hydroxypropyl methyl cellulose.
Daidaitawa.Hanyoyin ma'auni na yau da kullun sune ma'aunin danko na juyawa, ma'aunin dankowar capillary da ma'aunin dankowar faduwa.Hanyar ƙayyade hydroxypropyl methyl cellulose shine mannewar capillary.
Hanyar ƙayyade digiri, ta amfani da Uchs viscometer.Yawancin lokaci ƙayyadaddun maganin shine 2% maganin ruwa, tsarin shine: V=Kdt.V shine danko a cikin mpa.s da K shine madaidaicin viscometer.
D shine yawa a yawan zafin jiki kuma T shine lokacin daga sama zuwa ƙasa ta cikin viscometer a cikin daƙiƙa.Wannan hanyar aiki ta fi wahala, idan akwai kwayoyin da ba za su iya narkewa ba.
Kalmomi suna da sauƙin haifar da kurakurai, yana da wuya a gano ingancin hydroxypropyl methyl cellulose.Yanzu ana amfani da shi don auna danko na viscometer na jujjuya, wanda ake amfani da shi gabaɗaya a China.
Tsarin viscometer NDJ-1 shine η=KA.η shine danko, kuma a cikin mpa.s, K shine madaidaicin ma'aunin gani, kuma α shine karatun ma'anar viscometer.
Hydroxypropyl methyl cellulose 2% viscosity gwajin Hanyar:
1, wannan hanya ta dace da ƙayyadaddun ƙayyadaddun danko na ruwa maras Newton (wani bayani na polymer, dakatarwa, ruwa mai watsawa na emulsion ko bayani na surfactant, da dai sauransu).
2. Kayan aiki da kayan aiki
2.1 Rotary viscometer (NdJ-1 da NDJ-4 ana buƙatar Pharmacopoeia na kasar Sin)
2.2 Matsakaicin yawan zafin jiki na ruwan wanka akai-akai daidaitaccen zafin jiki 0.10C
2.3 Matsakaicin makin zafin jiki shine 0.20C, wanda ake tabbatarwa lokaci-lokaci.
2.4 Mitar Viscometers ta amfani da matakan daidaita mita (kamar NDJ-1 da NDJ-4) za a adana su.Daidaiton 1%.A
8. Og samfurin an auna daidai kuma an saka shi a cikin busassun busassun, mai tsayi mai tsayi 400mL.Ƙara kimanin 100mL na ruwan zafi na digiri 80-90 kuma motsawa don 10minti don raba
Ko'ina a tarwatsa, motsawa kuma ƙara ruwan sanyi zuwa 400mL gaba ɗaya.A halin yanzu, ci gaba da motsawa har tsawon minti 30 don yin maganin 2% (W/W), kuma saka shi a cikin firiji don wanka kankara don yin sanyi har sai ya zama kankara mai bakin ciki a saman.
Cire kuma saka a cikin tankin zazzabi akai-akai don kiyaye zafin jiki na tsakiya zuwa 20 ℃ 0.1 ℃.
3.1 Za a aiwatar da shigarwa da aiki na kayan aiki daidai da umarnin aiki na kayan aiki, kuma za a zaɓi rotor da rotor mai dacewa bisa ga kewayon danko na samfurin da aka gwada da kuma tanadin pharmacopoeia a ƙarƙashin rubutun samfur
Gudun juyawa.
3.2 Daidaita yawan zafin jiki na ruwan zafi bisa ga ƙaddara ƙarƙashin kowane abu na miyagun ƙwayoyi.
3.3 An sanya samfurin gwajin a cikin akwati da kayan aiki ya kayyade, kuma an auna kusurwar juyawa (a) bisa ga doka bayan minti 30 na yawan zafin jiki.Kashe motar kuma sake kunna shi don ƙaddara sau ɗaya
Bambanci tsakanin ma'auni bai kamata ya wuce 3% ba, in ba haka ba ya kamata a yi ma'auni na uku.
3.4 Lissafin ma'anar ma'anar gwaje-gwaje biyu bisa ga dabara don samun ƙarfin ɗanko na samfurin da aka gwada.
4. Yi rikodin kuma lissafta
4.1 Yi rikodin ƙirar viscometer rotary, lambar rotor da saurin da aka yi amfani da su, ƙimar viscometer akai-akai (K'darajar), da aka auna zafin jiki, da kowane ma'auni.Daraja
Ƙididdigar ƙididdiga ta 4.2
Dynamic danko (MPa”s) = Ka inda K shine ma'aunin ma'aunin viscometer akai-akai wanda aka auna shi tare da daidaitaccen ruwa sanannen danko kuma A shine kusurwar karkatarwa.
Lokacin aikawa: Mayu-18-2022